Bozzola M, Schimpff R M, Mingrat G, Ghini M
Pediatr Res. 1985 Feb;19(2):220-3. doi: 10.1203/00006450-198502000-00016.
Serum growth-promoting activity measured as [3H]thymidine incorporation into human activated lymphocytes and serum transferrin levels were measured during the perinatal period in newborns and mothers. Both thymidine activity (TA) and transferrin levels were significantly increased at the time of delivery in mothers compared to control women, and there was a progressive return to control levels in the first 5 postpartum days. A significant correlation was found between TA and placental weight. In the newborns, TA was low in cord blood after vaginal delivery but not in the cord blood from babies born by cesarean section. In premature newborns, TA was lower than in full term newborns. In all newborns during the first 24 postnatal hours, there was an increase in TA with levels rising above adult control values: levels in cord blood were positively correlated with birth weight but not with thymidine activity. These data afford complementary insights into the humoral controls of growth in newborn infants.
在新生儿和母亲的围产期，测量了以[3H]胸苷掺入人活化淋巴细胞来衡量的血清促生长活性以及血清转铁蛋白水平。与对照女性相比，母亲在分娩时胸苷活性（TA）和转铁蛋白水平均显著升高，且在产后头5天逐渐恢复到对照水平。发现TA与胎盘重量之间存在显著相关性。在新生儿中，经阴道分娩后脐带血中的TA较低，但剖宫产出生婴儿的脐带血中TA不低。早产儿的TA低于足月儿。在所有新生儿出生后的头24小时内，TA有所增加，水平高于成人对照值：脐带血中的水平与出生体重呈正相关，但与胸苷活性无关。这些数据为新生儿生长的体液控制提供了补充性见解。
