Faisal Debri Rizki, Noveyani Adistha Eka, Purwatiningsih Yuni, Lestyoningrum Sinta Dewi, Putro Wahyu Gito, Mikrajab Muhammad Agus, Nugraheni Wahyu Pudji
Research Centre for Public Health and Nutrition, Research Organisation for Health, National Research and Innovation Agency (BRIN), Bogor, West Java, Indonesia.
Faculty of Public Health, Universitas Jember, East Java, Indonesia.
Malays J Med Sci. 2024 Dec;31(6):112-125. doi: 10.21315/mjms2024.31.6.9. Epub 2024 Dec 31.
Southeast Asia (SEA) countries are characterised by a high burden of tuberculosis (TB). This research seeks to compile evidence of the prevalence and risk factors associated with TB among children in SEA countries. The searching of articles was conducted for four databases (PubMed, Scopus, Embase, and the Web of Science) published between 2013 and 2023 in the English language. The quality of articles was evaluated using the Joanna Briggs Institute (JBI) Critical Appraisal Tool for Assessment of Risk Bias for Cross-Sectional studies. This research was reported using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guideline. Eight studies were included in the systematic review. The prevalence of paediatric TB in SEA countries varies between 1.50% and 38.10%. Risk factors associated with the occurrence of TB in children include the nutritional status, the Bacillus Calmette-Guérin (BCG) vaccine status, close contact with TB patients, parental smoking behaviour, unhealthy living conditions, and socioeconomic determinants. The continued high prevalence of TB in several SEA countries, particularly among children, remains a significant public health concern. The various risk factors summarised can serve as a basis for implementing interventions aimed at reducing cases and preventing the transmission of TB among children.
东南亚国家的结核病负担较重。本研究旨在收集东南亚国家儿童结核病患病率及相关风险因素的证据。检索了2013年至2023年期间以英文发表在四个数据库（PubMed、Scopus、Embase和科学网）上的文章。使用乔安娜·布里格斯研究所（JBI）横断面研究风险偏倚评估的批判性评价工具对文章质量进行评估。本研究按照系统评价和Meta分析的首选报告项目（PRISMA）指南进行报告。八项研究纳入了系统评价。东南亚国家儿童结核病患病率在1.50%至38.10%之间。与儿童结核病发生相关的风险因素包括营养状况、卡介苗（BCG）接种状况、与结核病患者密切接触、父母吸烟行为、不健康的生活条件以及社会经济决定因素。在几个东南亚国家，尤其是儿童中，结核病的持续高患病率仍然是一个重大的公共卫生问题。总结的各种风险因素可为实施旨在减少病例和预防儿童结核病传播的干预措施提供依据。
