Universiti Teknologi MARA (UiTM) Sungai Buloh Campus, Faculty of Medicine, Department of Public Health Medicine, Selangor, Malaysia.
Universiti Teknologi MARA (UiTM) Puncak Alam Campus, Faculty of Medicine, Department of Pharmacy Practice and Clinical Pharmacy, Selangor, Malaysia.
Med J Malaysia. 2024 Jul;79(4):470-476.
Tuberculosis (TB) is a global public health issue. The Southeast Asian region grapples with numerous challenges in TB management, with loss to follow-up (LTFU) emerging as a critical barrier to effective control of the disease. This review synthesised published articles to identify socioeconomic factors contributing to the burden of TB losses for follow-up in Southeast Asia.
This scoping review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) framework developed by the Joanna Briggs Institute (JBI). A total of 10 studies were identified as eligible from the title and abstract review. The mixed method quality appraisal tool (MMAT) version 2018 was used to assess the quality of the included quantitative studies.
The results showed that poverty, unemployment, low education levels, migrant status, community support, male gender, substance abuse, and regional disparities significantly impact the occurrence of TB LTFU in Southeast Asia.
The findings have significant implications for public health in Southeast Asia. Addressing these socioeconomic barriers through community-based strategies, educational initiatives, and policy reforms is vital for improving treatment outcomes and overall public health.
结核病（TB）是一个全球性的公共卫生问题。东南亚地区在结核病管理方面面临诸多挑战，失访（LTFU）成为有效控制该疾病的一个关键障碍。本综述综合了已发表的文章，以确定导致东南亚结核病失访负担的社会经济因素。
本范围综述使用 Joanna Briggs 研究所（JBI）制定的系统评价和荟萃分析（PRISMA）首选报告项目框架进行。从标题和摘要审查中确定了 10 项符合条件的研究。使用混合方法质量评估工具（MMAT）版本 2018 评估纳入的定量研究的质量。
结果表明，贫困、失业、低教育水平、移民身份、社区支持、男性性别、药物滥用和地区差异显著影响东南亚结核病失访的发生。
这些发现对东南亚的公共卫生具有重要意义。通过基于社区的策略、教育举措和政策改革来解决这些社会经济障碍，对于改善治疗结果和整体公共卫生至关重要。
