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适当吊带张力的中段尿道吊带术是盆腔放疗后女性压力性尿失禁的有效治疗方法:一项病例系列的初步研究。

Mid-urethral sling with proper sling tension is an effective treatment for stress urinary incontinence in women after pelvic radiotherapy: a pilot study of case series.

作者信息

Guan Xing, Wang Fei, Zhang Di, Qiao Peng, Qin Yan, Wang Biao

机构信息

Department of Urology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.

Department of Urology, Guangxi Hospital Division of The First Affiliated Hospital, Sun Yat-sen University, Nanning, Guangxi, China.

出版信息

Front Surg. 2025 Jan 3;11:1475030. doi: 10.3389/fsurg.2024.1475030. eCollection 2024.

Abstract

BACKGROUND

At present, consensus on the management of female stress urinary incontinence (SUI) after pelvic radiotherapy is lacking. We aim to assess the clinical effects of mid-urethral sling (MUS) for the treatment of SUI after pelvic radiotherapy in women.

METHODS

We conducted a retrospective review of the clinical database of female with SUI after pelvic radiotherapy from June 2015 to February 2022. The clinical efficacy was evaluated by International Consultation on Incontinence Questionnaire-Short Form (ICI-Q-SF) questionnaire, maximum flow rate (Qmax) and postvoid residual (PVR) urine. All patients were reviewed postoperatively in an outpatient clinic.

RESULTS

We identified 26 patients with mean age of 59.35 ± 7.32 years. All the patients who suffered from SUI had a history of gynaecological malignancies and received pelvic radiotherapy. 21 patients (80.77%, 95% CI: 0.621-0.915) were considered to have successfully improved after surgery, the ICI-Q-SF scores were lower than the pre-operative at 2 weeks, 6 months and 1 year postoperatively ( < 0.01). After 1-year follow-up, none of the patients had mesh erosion.

CONCLUSION

SUI following radiotherapy for the treatment of pelvic malignancy can be challenging to manage. MUS is a highly effective and safe option for the treatment of SUI after radiotherapy, additionally, that proper sling tension is the key to the success of the procedure.

摘要

背景

目前,对于盆腔放疗后女性压力性尿失禁(SUI)的管理缺乏共识。我们旨在评估中段尿道吊带术(MUS)治疗女性盆腔放疗后SUI的临床效果。

方法

我们对2015年6月至2022年2月期间盆腔放疗后患有SUI的女性临床数据库进行了回顾性分析。通过国际尿失禁咨询问卷简表(ICI-Q-SF)、最大尿流率(Qmax)和残余尿量(PVR)评估临床疗效。所有患者术后均在门诊进行复查。

结果

我们确定了26例患者,平均年龄为59.35±7.32岁。所有患有SUI的患者均有妇科恶性肿瘤病史并接受过盆腔放疗。21例患者(80.77%,95%CI:0.621-0.915)术后被认为成功改善,术后2周、6个月和1年时ICI-Q-SF评分低于术前(<0.01)。随访1年后,无患者出现网片侵蚀。

结论

盆腔恶性肿瘤放疗后的SUI管理具有挑战性。MUS是放疗后SUI治疗的一种高效且安全的选择,此外,合适的吊带张力是手术成功的关键。

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Mid-urethral sling operations for stress urinary incontinence in women.女性压力性尿失禁的中段尿道吊带手术
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Mid-urethral sling operations for stress urinary incontinence in women.女性压力性尿失禁的经尿道中段吊带手术
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