Guan Xing, Wang Fei, Zhang Di, Qiao Peng, Qin Yan, Wang Biao
Department of Urology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Department of Urology, Guangxi Hospital Division of The First Affiliated Hospital, Sun Yat-sen University, Nanning, Guangxi, China.
Front Surg. 2025 Jan 3;11:1475030. doi: 10.3389/fsurg.2024.1475030. eCollection 2024.
At present, consensus on the management of female stress urinary incontinence (SUI) after pelvic radiotherapy is lacking. We aim to assess the clinical effects of mid-urethral sling (MUS) for the treatment of SUI after pelvic radiotherapy in women.
We conducted a retrospective review of the clinical database of female with SUI after pelvic radiotherapy from June 2015 to February 2022. The clinical efficacy was evaluated by International Consultation on Incontinence Questionnaire-Short Form (ICI-Q-SF) questionnaire, maximum flow rate (Qmax) and postvoid residual (PVR) urine. All patients were reviewed postoperatively in an outpatient clinic.
We identified 26 patients with mean age of 59.35 ± 7.32 years. All the patients who suffered from SUI had a history of gynaecological malignancies and received pelvic radiotherapy. 21 patients (80.77%, 95% CI: 0.621-0.915) were considered to have successfully improved after surgery, the ICI-Q-SF scores were lower than the pre-operative at 2 weeks, 6 months and 1 year postoperatively ( < 0.01). After 1-year follow-up, none of the patients had mesh erosion.
SUI following radiotherapy for the treatment of pelvic malignancy can be challenging to manage. MUS is a highly effective and safe option for the treatment of SUI after radiotherapy, additionally, that proper sling tension is the key to the success of the procedure.
目前,对于盆腔放疗后女性压力性尿失禁(SUI)的管理缺乏共识。我们旨在评估中段尿道吊带术(MUS)治疗女性盆腔放疗后SUI的临床效果。
我们对2015年6月至2022年2月期间盆腔放疗后患有SUI的女性临床数据库进行了回顾性分析。通过国际尿失禁咨询问卷简表(ICI-Q-SF)、最大尿流率(Qmax)和残余尿量(PVR)评估临床疗效。所有患者术后均在门诊进行复查。
我们确定了26例患者,平均年龄为59.35±7.32岁。所有患有SUI的患者均有妇科恶性肿瘤病史并接受过盆腔放疗。21例患者(80.77%,95%CI:0.621-0.915)术后被认为成功改善,术后2周、6个月和1年时ICI-Q-SF评分低于术前(<0.01)。随访1年后,无患者出现网片侵蚀。
盆腔恶性肿瘤放疗后的SUI管理具有挑战性。MUS是放疗后SUI治疗的一种高效且安全的选择,此外,合适的吊带张力是手术成功的关键。