Ogbebor Irene Omoisi, Benlance Edetanlen Ekaniyere, Igbinosa Lawrence Osarhiemen
Department of Family Dentistry, University of Benin Teaching Hospital, Benin-city, Edo State, Nigeria.
Department of Oral and Maxillofacial Surgery, University of Benin Teaching Hospital, Benin-City, Edo State, Nigeria.
Natl J Maxillofac Surg. 2024 Sep-Dec;15(3):387-391. doi: 10.4103/njms.njms_195_23. Epub 2024 Nov 16.
Postoperative throat complications (POTCs) are common and distressing to patients; consensus on their optimum treatment is unclear.
The aim of the study was to determine the efficacy of a steroid-soaked throat pack on POTCs following oral and maxillofacial surgery.
This was a randomized, triple-blinded, controlled clinical study design on all consecutive patients who had endotracheal intubation and pharyngeal throat packs following major oral and maxillofacial surgery. They were randomized into experimental (steroid) and control (normal saline) groups. The experimental group had their throat packs soaked with 10 ml aqueous solution of 100 mg hydrocortisone, while the control group had their throat pack soaked with 10 ml of 0.9% normal saline. The data were clinicodemographic, type of throat pack, postoperative sore throat, dysphagia, hoarseness, and cough. Both descriptive and inferential statistics were performed. values < 0.05 were considered significant.
A total of 48 patients comprising 24 in each group participated fully in the study. The mean age and the age range of the participants were 37.3 ± 15.6 years and 18-65 years, respectively. There was no significant difference between the two groups in the demographic and surgical characteristics studied ( > 0.05). There was a significantly higher prevalence of postoperative sore throat and dysphagia among the normal saline group compared to the steroid group ( < 0.05). There was no significant difference in the prevalence of postoperative cough and hoarseness between the steroid and normal saline groups ( > 0.05).
The use of a steroid-soaked throat pack was found to be more efficacious in the reduction of the prevalence of postoperative sore throat and dysphagia but did not affect the prevalence of postoperative cough and hoarseness among patients that had major oral and maxillofacial surgical procedures.
术后咽喉并发症（POTCs）很常见，且令患者痛苦；关于其最佳治疗方法尚无共识。
本研究的目的是确定类固醇浸泡的咽喉敷料对口腔颌面外科手术后POTCs的疗效。
这是一项针对所有在大型口腔颌面外科手术后接受气管插管和咽部咽喉敷料的连续患者的随机、三盲、对照临床研究设计。他们被随机分为实验组（类固醇）和对照组（生理盐水）。实验组的咽喉敷料用100毫克氢化可的松的10毫升水溶液浸泡，而对照组的咽喉敷料用10毫升0.9%生理盐水浸泡。数据包括临床人口统计学、咽喉敷料类型、术后咽痛、吞咽困难、声音嘶哑和咳嗽。进行了描述性和推断性统计。P值<0.05被认为具有统计学意义。
共有48名患者，每组24名，充分参与了研究。参与者的平均年龄和年龄范围分别为37.3±15.6岁和18 - 65岁。在研究的人口统计学和手术特征方面，两组之间没有显著差异（P>0.05）。与类固醇组相比，生理盐水组术后咽痛和吞咽困难的患病率显著更高（P<0.05）。类固醇组和生理盐水组术后咳嗽和声音嘶哑的患病率没有显著差异（P>0.05）。
在接受大型口腔颌面外科手术的患者中，使用类固醇浸泡的咽喉敷料在降低术后咽痛和吞咽困难的患病率方面更有效，但不影响术后咳嗽和声音嘶哑的患病率。
