Doukumo Dm, Faponle Af, Adenekan At, Olateju Soa, Bolaji Bo
Departments of Anaesthesia, Obafemi Awolowo University Teaching Hospital, Ile-Ife, Nigeria.
Departments of Anaesthesia, Obafemi Awolowo University, Ile-Ife, Nigeria.
J West Afr Coll Surg. 2011 Jul;1(3):44-61.
Tracheal intubation for general anaesthesia is often associated with postoperative sore throat, hoarseness and cough which can be distressing to patients. We compared the effects of lidocaine and K-Y jellies on postoperative sore throat, cough and hoarseness of voice following endotracheal anaesthesia.
Ninety-two ASA I or II patients scheduled for elective surgery under endotracheal general anaesthesia were randomly allocated into two groups. Tracheal tubes were lubricated with either 2% lidocaine jelly (LJ) or K-Y jelly (KYJ) for the groups and the patients were interviewed at 1, 12 and 24 hours post extubation.
The mean scores for sore throat were lower in the KYJ group than the LJ group but this was only statistically significant at 12 hours (p = 0.02). The incidence of sore throat, hoarseness and cough were also lower in the KYJ than in the LJ group but these were not significant. While the incidence of sore throat was comparable among both sexes in the LJ group, it was higher in females (55.6%) than in males (18.8%) in the KYJ group (p = 0.02). Whereas in patients older than 30 years the incidence of sore throat, hoarseness and cough were similar in both groups, in patients less than 30 years, there were significant differences (p = 0.01 and 0.02 respectively). The incidence of side effects was similar in both groups irrespective of duration of intubation.
K-Y jelly is superior to lidocaine jelly in preventing postoperative sore throat, and in reducing the incidence of hoarseness of voice and cough. Postopearive throat complaints are more common in females than males.
全身麻醉气管插管常伴有术后咽痛、声音嘶哑和咳嗽,这会给患者带来痛苦。我们比较了利多卡因和K-Y凝胶对气管内麻醉后术后咽痛、咳嗽和声音嘶哑的影响。
92例计划在气管内全身麻醉下进行择期手术的ASA I或II级患者被随机分为两组。分别用2%利多卡因凝胶(LJ)或K-Y凝胶(KYJ)润滑气管导管,在拔管后1、12和24小时对患者进行访谈。
KYJ组咽痛的平均评分低于LJ组,但仅在12小时时有统计学意义(p = 0.02)。KYJ组咽痛、声音嘶哑和咳嗽的发生率也低于LJ组,但差异无统计学意义。LJ组中男女咽痛发生率相当,而KYJ组中女性(55.6%)高于男性(18.8%)(p = 0.02)。30岁以上患者中两组咽痛、声音嘶哑和咳嗽的发生率相似,而30岁以下患者中两组存在显著差异(分别为p = 0.01和0.02)。两组副作用发生率相似,与插管持续时间无关。
K-Y凝胶在预防术后咽痛、降低声音嘶哑和咳嗽发生率方面优于利多卡因凝胶。术后咽痛在女性中比男性更常见。