• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

急性髓系白血病中以肉眼血尿为表现的膀胱髓系肉瘤

Macroscopic Hematuria Revealing Bladder Myeloid Sarcoma in Acute Myeloid Leukemia.

作者信息

Halloumi Omar, Sebastian Wittnebel, Harb Mirvate, Trépant Anne Laure, Andreozzi Fabio

机构信息

Department of Clinical Hematology and Cellular Therapy, Centre Hospitalier Universitaire (CHU) Souss-Massa, Agadir, MAR.

Faculty of Medicine and Pharmacy, Université Ibn Zohr, Agadir, MAR.

出版信息

Cureus. 2024 Dec 17;16(12):e75912. doi: 10.7759/cureus.75912. eCollection 2024 Dec.

DOI:10.7759/cureus.75912
PMID:39830569
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11739638/
Abstract

Acute myeloid leukemia (AML) can be presented with extramedullary manifestations, more frequently involving skin and rarely other sites, such as the urinary tract. We report the case of a 37-year-old male patient with a history of testicular cancer who presented to the emergency department with cytopenias and hematuria. Bone marrow analysis diagnosed AML (French-American-British(FAB) classificationM4 subtype, karyotype showing inv16). A diagnostic workup for hematuria revealed a bladder mass that underwent biopsy. Histopathology revealed myeloid sarcoma. The patient was treated with standard induction chemotherapy, followed by consolidation therapy including allogeneic stem cell transplantation, which resulted in complete remission of AML.

摘要

急性髓系白血病（AML）可出现髓外表现，更常见累及皮肤，很少累及其他部位，如泌尿道。我们报告一例37岁男性患者，有睾丸癌病史，因血细胞减少和血尿就诊于急诊科。骨髓分析诊断为AML（法国-美国-英国（FAB）分类M4亚型，核型显示inv16）。对血尿进行的诊断性检查发现膀胱肿物并进行了活检。组织病理学显示为髓系肉瘤。该患者接受了标准诱导化疗，随后进行了包括异基因干细胞移植在内的巩固治疗，结果AML完全缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcd6/11739638/5a2e8f5579b0/cureus-0016-00000075912-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcd6/11739638/74cf5146f8ab/cureus-0016-00000075912-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcd6/11739638/1e76ef57a323/cureus-0016-00000075912-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcd6/11739638/5a2e8f5579b0/cureus-0016-00000075912-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcd6/11739638/74cf5146f8ab/cureus-0016-00000075912-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcd6/11739638/1e76ef57a323/cureus-0016-00000075912-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcd6/11739638/5a2e8f5579b0/cureus-0016-00000075912-i03.jpg

相似文献

1
Macroscopic Hematuria Revealing Bladder Myeloid Sarcoma in Acute Myeloid Leukemia.急性髓系白血病中以肉眼血尿为表现的膀胱髓系肉瘤
Cureus. 2024 Dec 17;16(12):e75912. doi: 10.7759/cureus.75912. eCollection 2024 Dec.
2
Bladder granulocytic sarcoma in a child: case report and literature review.儿童膀胱粒细胞肉瘤：病例报告及文献综述
Turk J Pediatr. 2022;64(1):152-159. doi: 10.24953/turkjped.2020.275.
3
Myeloid sarcoma without circulating leukemia mimicking gastrointestinal malignancy and lymphoma.无循环白血病的髓系肉瘤，酷似胃肠道恶性肿瘤和淋巴瘤。
Hematol Rep. 2018 Jun 14;10(2):7040. doi: 10.4081/hr.2018.7040. eCollection 2018 May 14.
4
Myeloid sarcoma of the vulva post-bone marrow transplant presenting as isolated extramedullary relapse in a patient with acute myeloid leukemia.骨髓移植后外阴髓系肉瘤表现为急性髓系白血病患者孤立性髓外复发。
Hematol Oncol Stem Cell Ther. 2012;5(2):118-21. doi: 10.5144/1658-3876.2012.118.
5
Breast myeloid sarcoma presenting as a palpable breast lump after allogeneic stem cell transplantation for acute myelomonocytic leukemia: a rare case report.异基因造血干细胞移植后发生的急性髓单核细胞白血病相关乳腺髓系肉瘤：1 例罕见病例报告
World J Surg Oncol. 2021 Sep 27;19(1):289. doi: 10.1186/s12957-021-02399-9.
6
Myeloid Sarcoma of the Paranasal Sinuses in a Patient with Acute Myeloid Leukemia.一名急性髓系白血病患者的鼻窦髓系肉瘤
Tohoku J Exp Med. 2018 Oct;246(2):141-146. doi: 10.1620/tjem.246.141.
7
Extramedullary Acute Myeloid Leukemia of the Renal Pelvis: Insights into a Visceral Niche.肾盂外急性髓系白血病：内脏龛的深入了解。
Acta Haematol. 2021;144(3):297-301. doi: 10.1159/000508526. Epub 2020 Aug 19.
8
Chloroma of the Bladder: A Case Report of Leukemia Progression Presenting as Hematuria.膀胱绿色瘤：一例以血尿为表现的白血病进展病例报告
Case Rep Oncol. 2021 Sep 21;14(3):1366-1372. doi: 10.1159/000518529. eCollection 2021 Sep-Dec.
9
Widespread myeloid sarcoma with KMT2A rearrangement involving the testis, oral cavity, heart, kidney and gallbladder without bone marrow involvement.广泛播散的髓系肉瘤伴KMT2A重排，累及睾丸、口腔、心脏、肾脏和胆囊，无骨髓受累。
Leuk Res Rep. 2022 Sep 7;18:100349. doi: 10.1016/j.lrr.2022.100349. eCollection 2022.
10
Myeloid sarcoma of the prostate revealed by urinary retention: a case report.以尿潴留为表现的前列腺髓系肉瘤：1例报告
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.06.2008.0240. Epub 2009 Mar 2.

本文引用的文献

1
Isolated myeloid sarcoma in the urinary bladder: A cases report.膀胱孤立性髓系肉瘤：一例病例报告。
Asian J Surg. 2024 Apr;47(4):1928-1929. doi: 10.1016/j.asjsur.2023.12.074. Epub 2024 Jan 11.
2
Myeloid sarcoma of the urinary bladder as the presenting feature of secondary acute myeloid leukemia, successfully treated with venetoclax and azacitidine.膀胱髓系肉瘤作为继发性急性髓系白血病的首发表现，经维奈克拉和阿扎胞苷成功治疗。
Ann Hematol. 2024 Feb;103(2):671-672. doi: 10.1007/s00277-023-05529-3. Epub 2023 Nov 9.
3
Bladder granulocytic sarcoma in a child: case report and literature review.
儿童膀胱粒细胞肉瘤：病例报告及文献综述
Turk J Pediatr. 2022;64(1):152-159. doi: 10.24953/turkjped.2020.275.
4
Bladder Myeloid Sarcoma with mutated Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap syndrome: Response to Decitabine-Venetoclax regimen.伴有骨髓增生异常综合征/骨髓增殖性肿瘤重叠综合征突变的膀胱髓系肉瘤：对地西他滨-维奈克拉方案的反应
Leuk Res Rep. 2021 Dec 14;17:100286. doi: 10.1016/j.lrr.2021.100286. eCollection 2022.
5
Chloroma of the Bladder: A Case Report of Leukemia Progression Presenting as Hematuria.膀胱绿色瘤：一例以血尿为表现的白血病进展病例报告
Case Rep Oncol. 2021 Sep 21;14(3):1366-1372. doi: 10.1159/000518529. eCollection 2021 Sep-Dec.
6
Clinical outcome of myeloid sarcoma in adult patients and effect of allogeneic stem cell transplantation. Results from a multicenter survey.成年患者髓系肉瘤的临床结局及异基因干细胞移植的效果。一项多中心调查结果
Leuk Res. 2017 Feb;53:74-81. doi: 10.1016/j.leukres.2016.12.003. Epub 2016 Dec 20.
7
Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel.成人急性髓系白血病的诊断与管理：2017年国际专家小组的欧洲白血病网络（ELN）建议
Blood. 2017 Jan 26;129(4):424-447. doi: 10.1182/blood-2016-08-733196. Epub 2016 Nov 28.
8
Myeloid Sarcoma of the Bladder in the Setting of Refractory Anemia with Excess Blasts-2 (RAEB-2).
W V Med J. 2015 Nov-Dec;111(6):34-6.
9
Granulocytic sarcoma of bladder in an 18-mo-old child with acute myeloid leukemia.一名18个月大的急性髓性白血病患儿发生膀胱粒细胞肉瘤。
Indian J Pediatr. 2014 Oct;81(10):1118-9. doi: 10.1007/s12098-014-1371-1. Epub 2014 Feb 25.
10
Unusual presentation of bladder myeloid sarcoma causing acute renal failure: case report and review of the literature.膀胱髓系肉瘤导致急性肾衰竭的罕见表现：病例报告及文献复习
Clin Adv Hematol Oncol. 2013 Jun;11(6):388-93.