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患者检查床对心肌灌注显像单光子发射计算机断层扫描中衰减的影响

On the Effect of the Patient Table on Attenuation in Myocardial Perfusion Imaging SPECT.

作者信息

Huxohl Tamino, Patel Gopesh, Burchert Wolfgang

机构信息

Institute of Radiology, Nuclear Medicine and Molecular Imaging, Heart and Diabetes Center North Rhine-Westphalia, University Hospital (Ruhr University Bochum), Medical Faculty OWL (Bielefeld University), Bad Oeynhausen, Germany.

出版信息

EJNMMI Phys. 2025 Jan 20;12(1):3. doi: 10.1186/s40658-024-00713-4.

DOI:10.1186/s40658-024-00713-4
PMID:39832088
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11746982/
Abstract

BACKGROUND

The topic of the effect of the patient table on attenuation in myocardial perfusion imaging (MPI) SPECT is gaining new relevance due to deep learning methods. Existing studies on this effect are old, rare and only consider phantom measurements, not patient studies. This study investigates the effect of the patient table on attenuation based on the difference between reconstructions of phantom scans and polar maps of patient studies.

METHODS

Jaszczak phantom scans are acquired according to quality control and MPI procedures. An algorithm is developed to automatically remove the patient table from the CT for attenuation correction. The scans are then reconstructed with attenuation correction either with or without the patient table in the CT. The reconstructions are compared qualitatively and on the basis of their percentage difference. In addition, a small retrospective cohort of 15 patients is examined by comparing the resulting polar maps. Polar maps are compared qualitatively and based on the segment perfusion scores.

RESULTS

The phantom reconstructions look qualitatively similar in both the quality control and MPI procedures. The percentage difference is highest in the lower part of the phantom, but it always remains below 17.5%. Polar maps from patient studies also look qualitatively similar. Furthermore, the segment scores are not significantly different (p=0.83).

CONCLUSIONS

The effect of the patient table on attenuation in MPI SPECT is negligible.

摘要

背景

由于深度学习方法,患者检查床对心肌灌注成像(MPI)单光子发射计算机断层扫描(SPECT)中衰减的影响这一话题正变得越来越重要。现有的关于这种影响的研究年代久远、数量稀少,并且仅考虑了模体测量,而非患者研究。本研究基于模体扫描重建与患者研究极坐标图之间的差异,调查患者检查床对衰减的影响。

方法

根据质量控制和MPI程序获取Jaszczak模体扫描图像。开发了一种算法,用于在CT图像中自动去除患者检查床以进行衰减校正。然后对扫描图像进行重建,在CT图像中有或没有患者检查床的情况下进行衰减校正。对重建图像进行定性比较,并基于它们的百分比差异进行比较。此外,通过比较15例患者的极坐标图,对一个小型回顾性队列进行研究。对极坐标图进行定性比较,并基于节段灌注评分进行比较。

结果

在质量控制和MPI程序中,模体重建在定性上看起来相似。百分比差异在模体下部最高,但始终保持在17.5%以下。患者研究的极坐标图在定性上也看起来相似。此外,节段评分没有显著差异(p = 0.83)。

结论

患者检查床对MPI SPECT中衰减的影响可以忽略不计。

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本文引用的文献

1
Deep learning approximation of attenuation maps for myocardial perfusion SPECT with an IQSPECT collimator.使用IQSPECT准直器对心肌灌注单光子发射计算机断层扫描衰减图进行深度学习近似。
EJNMMI Phys. 2023 Aug 28;10(1):49. doi: 10.1186/s40658-023-00568-1.
2
Myocardial perfusion SPECT in Germany from 2012 to 2021: insights into development and quality indicators.德国 2012 年至 2021 年心肌灌注 SPECT:发展洞察与质量指标。
Eur J Nucl Med Mol Imaging. 2023 May;50(6):1621-1628. doi: 10.1007/s00259-023-06129-z. Epub 2023 Feb 13.
3
Deep Learning-Based Attenuation Correction Improves Diagnostic Accuracy of Cardiac SPECT.
深度学习衰减校正提高心脏 SPECT 诊断准确性。
J Nucl Med. 2023 Mar;64(3):472-478. doi: 10.2967/jnumed.122.264429. Epub 2022 Sep 22.
4
Cross-vender, cross-tracer, and cross-protocol deep transfer learning for attenuation map generation of cardiac SPECT.跨供应商、跨示踪剂和跨协议的心脏 SPECT 衰减图生成的深度迁移学习。
J Nucl Cardiol. 2022 Dec;29(6):3379-3391. doi: 10.1007/s12350-022-02978-7. Epub 2022 Apr 26.
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Direct and indirect strategies of deep-learning-based attenuation correction for general purpose and dedicated cardiac SPECT.基于深度学习的通用和专用心脏 SPECT 衰减校正的直接和间接策略。
Eur J Nucl Med Mol Imaging. 2022 Jul;49(9):3046-3060. doi: 10.1007/s00259-022-05718-8. Epub 2022 Feb 16.
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CT-free attenuation correction for dedicated cardiac SPECT using a 3D dual squeeze-and-excitation residual dense network.使用三维双挤压激发残差密集网络的专用心脏 SPECT 无 CT 衰减校正。
J Nucl Cardiol. 2022 Oct;29(5):2235-2250. doi: 10.1007/s12350-021-02672-0. Epub 2021 Jun 3.
7
Fisher information analysis of list-mode SPECT emission data for joint estimation of activity and attenuation distribution.用于联合估计活度和衰减分布的列表模式单光子发射计算机断层显像(SPECT)发射数据的费舍尔信息分析
Inverse Probl. 2020 Aug;36(8). doi: 10.1088/1361-6420/ab958b. Epub 2020 Aug 20.
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Deep learning-based attenuation map generation for myocardial perfusion SPECT.基于深度学习的心肌灌注单光子发射计算机断层扫描衰减映射生成
Eur J Nucl Med Mol Imaging. 2020 Sep;47(10):2383-2395. doi: 10.1007/s00259-020-04746-6. Epub 2020 Mar 26.
9
Value of attenuation correction in stress-only myocardial perfusion imaging using CZT-SPECT.使用碲锌镉单光子发射计算机断层扫描(CZT-SPECT)进行仅负荷心肌灌注成像时衰减校正的价值。
J Nucl Cardiol. 2017 Apr;24(2):395-401. doi: 10.1007/s12350-015-0374-2. Epub 2016 Jan 15.
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SPECT/CT physical principles and attenuation correction.单光子发射计算机断层扫描/计算机断层扫描(SPECT/CT)的物理原理与衰减校正
J Nucl Med Technol. 2008 Mar;36(1):1-10. doi: 10.2967/jnmt.107.046839. Epub 2008 Feb 20.