Mäenpää Heidi, Ojala Tiina, Tainio Juuso, Arokoski Jari, Jahnukainen Timo
Department of Rehabilitation, New Children's Hospital, Helsinki University Hospital, Helsinki, Finland and University of Helsinki, Helsinki, Finland.
Department of Pediatric Cardiology, New Children's Hospital, Helsinki University Hospital, Helsinki, Finland and University of Helsinki, Helsinki, Finland.
Clin Transplant. 2025 Jan;39(1):e70061. doi: 10.1111/ctr.70061.
Physical performance capacity (PPC) of pediatric heart transplant (HT) recipients is reportedly low to normal, and longitudinal follow-up of these patients is recommended. However, no recommendation for a follow-up method is available. In this study, the correlation between the 6-min walk test (6MWT), various clinical parameters, and a physical performance test set was evaluated to develop a simple follow-up tool for PPC.
Fifteen pediatric HT patients and 392 historical controls were tested at a median age of 15.4 years. PPC was tested with a 6MWT and a physical performance test set consisting of six different components assessing muscle endurance, strength, speed, and flexibility.
Controls outperformed recipients across all test domains except the leg lift and sit-and-reach test. The 6MWT distance correlated well with the physical performance test set results; the correlations were with leg lift (r = 0.622, p = <0.05), repeated squatting (r = 0.851, p = <0.001, sit-up (r = 0.738, p = <0.05), back extension (r = 0.747, p ≤ 0.001), and total physical performance capacity (r = 0.873, p = <0.001). Indexed 6MWT results or total physical performance capacity set had no statistically significant associations with any of the clinical parameters tested.
Our study supports recent findings suggesting that the 6MWT is a suitable method for longitudinal follow-up in children with HT. We recommend performing the 6MWT annually in these patients, to be used to motivate and encourage them to enhance their physical activity.
据报道，小儿心脏移植（HT）受者的身体运动能力（PPC）处于低至正常水平，建议对这些患者进行长期随访。然而，目前尚无关于随访方法的建议。在本研究中，评估了6分钟步行试验（6MWT）、各种临床参数与一套身体运动能力测试之间的相关性，以开发一种用于PPC的简单随访工具。
对15例小儿HT患者和392例历史对照者进行测试，中位年龄为15.4岁。通过6MWT和一套身体运动能力测试对PPC进行测试，该测试包括六个不同部分，评估肌肉耐力、力量、速度和柔韧性。
除抬腿和坐位体前屈测试外，对照组在所有测试领域的表现均优于受者。6MWT距离与身体运动能力测试结果相关性良好；与抬腿（r = 0.622，p = <0.05）、重复深蹲（r = 0.851，p = <0.001）、仰卧起坐（r = 0.738，p = <0.05）、背部伸展（r = 0.747，p ≤ 0.001）以及总身体运动能力（r = 0.873，p = <0.001）相关。6MWT结果指数或总身体运动能力测试结果与所测试的任何临床参数均无统计学显著关联。
我们的研究支持最近的研究结果，表明6MWT是小儿HT患者长期随访的合适方法。我们建议每年对这些患者进行6MWT测试，以激励和鼓励他们增加身体活动。
