Prasad A
Pharmacol Biochem Behav. 1985 Feb;22(2):347-8. doi: 10.1016/0091-3057(85)90403-4.
Eight patients with chronic Obsessive-Compulsive Neurosis were subjected to Trazodone, an antidepressant acting on the serotinergic system. After 4 weeks of treatment, 6 showed significant reduction in the obsessional symptoms which was sustained after a 6-week follow-up. The 2 patients who did not show improvement had a significantly higher trait score than the others on psychometric ratings.
八名患有慢性强迫性神经症的患者接受了曲唑酮治疗,曲唑酮是一种作用于血清素能系统的抗抑郁药。治疗4周后,6名患者的强迫症状显著减轻,在6周的随访后仍持续改善。在心理测量评分中,未显示出改善的2名患者的特质得分明显高于其他患者。