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曲唑酮作为一种抗强迫药物的疗效。

Efficacy of trazodone as an anti obsessional agent.

作者信息

Prasad A

出版信息

Pharmacol Biochem Behav. 1985 Feb;22(2):347-8. doi: 10.1016/0091-3057(85)90403-4.

DOI:10.1016/0091-3057(85)90403-4
PMID:3983224
Abstract

Eight patients with chronic Obsessive-Compulsive Neurosis were subjected to Trazodone, an antidepressant acting on the serotinergic system. After 4 weeks of treatment, 6 showed significant reduction in the obsessional symptoms which was sustained after a 6-week follow-up. The 2 patients who did not show improvement had a significantly higher trait score than the others on psychometric ratings.

摘要

八名患有慢性强迫性神经症的患者接受了曲唑酮治疗,曲唑酮是一种作用于血清素能系统的抗抑郁药。治疗4周后,6名患者的强迫症状显著减轻,在6周的随访后仍持续改善。在心理测量评分中,未显示出改善的2名患者的特质得分明显高于其他患者。

相似文献

1
Efficacy of trazodone as an anti obsessional agent.曲唑酮作为一种抗强迫药物的疗效。
Pharmacol Biochem Behav. 1985 Feb;22(2):347-8. doi: 10.1016/0091-3057(85)90403-4.
2
Efficacy of trazodone as an anti-obsessional agent.
Neuropsychobiology. 1986;15 Suppl 1:19-21. doi: 10.1159/000118274.
3
Obsessive-compulsive disorder and trazodone.强迫症与曲唑酮
Am J Psychiatry. 1984 Apr;141(4):612-3. doi: 10.1176/ajp.141.4.612b.
4
Two cases of obsessive-compulsive disorder with depression responsive to trazodone.两例对曲唑酮有反应的伴有抑郁的强迫症病例。
J Nerv Ment Dis. 1985 Jul;173(7):432-3. doi: 10.1097/00005053-198507000-00007.
5
A double-blind, placebo controlled study of trazodone in patients with obsessive-compulsive disorder.
J Clin Psychopharmacol. 1992 Jun;12(3):156-62.
6
Trazodone, a new antidepressant: efficacy and safety in endogenous depression.曲唑酮,一种新型抗抑郁药:在内源性抑郁症中的疗效与安全性。
J Clin Psychiatry. 1979 Sep;40(9):390-5.
7
Chlorimipramine therapy for obsessive-compulsive neurosis.氯米帕明治疗强迫性神经症
Am J Psychiatry. 1979 May;136(5):700-1. doi: 10.1176/ajp.136.5.700.
8
Trazodone-fluoxetine combination for treatment of obsessive-compulsive disorder.曲唑酮-氟西汀联合用药治疗强迫症
Am J Psychiatry. 1989 Dec;146(12):1637. doi: 10.1176/ajp.146.12.1637b.
9
Trazodone in the treatment of neurosis--an uncontrolled clinical study.曲唑酮治疗神经症——一项非对照临床研究。
Psychopharmacol Bull. 1976 Jan;12(1):21-2.
10
Treatment of geriatric depression with trazodone, imipramine, and placebo: a double-blind study.曲唑酮、丙咪嗪和安慰剂治疗老年抑郁症:一项双盲研究。
J Clin Psychiatry. 1980 Jun;41(6):216-20.

引用本文的文献

1
Trazodone effects on developing brain.曲唑酮对发育中大脑的影响。
Transl Psychiatry. 2021 Feb 1;11(1):85. doi: 10.1038/s41398-021-01217-w.
2
Obsessive-compulsive disorder in elderly patients.老年患者的强迫症
Drugs Aging. 1995 Dec;7(6):438-48. doi: 10.2165/00002512-199507060-00004.
3
Trazodone. A review of its pharmacology, therapeutic use in depression and therapeutic potential in other disorders.曲唑酮。对其药理学、在抑郁症中的治疗用途及在其他疾病中的治疗潜力的综述。
Drugs Aging. 1994 Apr;4(4):331-55. doi: 10.2165/00002512-199404040-00006.