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颈动脉蹼内复发性血栓形成:强调及时手术干预的重要性。病例说明。

Recurrent thrombus formation in a carotid web: highlighting the importance of timely surgical intervention. Illustrative case.

作者信息

Takahashi Toshihide, Yanaka Kiyoyuki, Saura Minami, Aiyama Hitoshi, Takahashi Nobuyuki, Marushima Aiki, Matsumaru Yuji, Ishikawa Eiichi

机构信息

Department of Neurosurgery, Tsukuba Memorial Hospital, Tsukuba, Ibaraki, Japan.

Department of Radiology, Tsukuba Memorial Hospital, Tsukuba, Ibaraki, Japan.

出版信息

J Neurosurg Case Lessons. 2025 Jan 20;9(3). doi: 10.3171/CASE24682.

DOI:10.3171/CASE24682
PMID:39832306
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11744690/
Abstract

BACKGROUND

Carotid webs are rare nonatherosclerotic disorders in the carotid artery and are increasingly recognized as factors of ischemic stroke in the young population. Asymptomatic webs can be treated with antithrombotic therapy, whereas symptomatic cases frequently require surgical interventions, including carotid endarterectomy (CEA). However, guidelines for the optimal timing of these treatments remain unestablished, especially compared to atherosclerotic stenotic lesions, due to the rarity of carotid webs.

OBSERVATIONS

A 50-year-old female patient had a carotid web-induced left hemispheric ischemic stroke. Mechanical thrombectomy successfully restored blood flow, but a thrombus reformed in the carotid web within 1 month following the procedure. This caused early CEA, during which the carotid web and thrombus were removed. This case highlights rapid thrombus reformation, indicating that some carotid webs can be more unstable than previously thought.

LESSONS

This case emphasizes the importance of timely surgical intervention in symptomatic carotid webs to prevent recurrent strokes. Additionally, antithrombotic therapy can manage asymptomatic webs, but surgical treatment may be required in unstable cases. Thus, further studies are warranted to establish standardized treatment guidelines for carotid webs. https://thejns.org/doi/10.3171/CASE24682.

摘要

背景

颈动脉纤维网是颈动脉罕见的非动脉粥样硬化性疾病,越来越被认为是年轻人群缺血性卒中的病因。无症状的纤维网可采用抗血栓治疗,而有症状的病例通常需要手术干预,包括颈动脉内膜切除术(CEA)。然而,由于颈动脉纤维网罕见,与动脉粥样硬化性狭窄病变相比,这些治疗的最佳时机指南仍未确立。

观察

一名50岁女性患者发生了由颈动脉纤维网引起的左半球缺血性卒中。机械取栓成功恢复了血流,但术后1个月内颈动脉纤维网内血栓再次形成。这导致了早期CEA,术中切除了颈动脉纤维网和血栓。该病例突出了血栓的快速再形成,表明一些颈动脉纤维网可能比之前认为的更不稳定。

经验教训

该病例强调了对有症状的颈动脉纤维网及时进行手术干预以预防复发性卒中的重要性。此外,抗血栓治疗可用于处理无症状的纤维网,但不稳定的病例可能需要手术治疗。因此,有必要进行进一步研究以建立颈动脉纤维网的标准化治疗指南。https://thejns.org/doi/10.3171/CASE24682 。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964e/11744690/7c8ba9c8bccb/CASE24682_figure_5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964e/11744690/67865dc35545/CASE24682_figure_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964e/11744690/a6dda5d98285/CASE24682_figure_2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964e/11744690/b20049cc10c0/CASE24682_figure_3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964e/11744690/9b161e5affb4/CASE24682_figure_4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964e/11744690/7c8ba9c8bccb/CASE24682_figure_5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964e/11744690/67865dc35545/CASE24682_figure_1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964e/11744690/a6dda5d98285/CASE24682_figure_2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964e/11744690/b20049cc10c0/CASE24682_figure_3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964e/11744690/9b161e5affb4/CASE24682_figure_4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/964e/11744690/7c8ba9c8bccb/CASE24682_figure_5.jpg

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本文引用的文献

1
Spontaneous asymptomatic common carotid artery dissection resembling a carotid web: illustrative case.酷似颈动脉蹼的自发性无症状颈总动脉夹层:病例报告
J Neurosurg Case Lessons. 2024 Sep 9;8(11). doi: 10.3171/CASE24344.
2
Subjects with carotid webs demonstrate pro-thrombotic hemodynamics compared to subjects with carotid atherosclerosis.与颈动脉粥样硬化患者相比,颈动脉膜患者表现出促血栓形成的血液动力学特征。
Sci Rep. 2024 May 2;14(1):10092. doi: 10.1038/s41598-024-60666-7.
3
Histopathological Examination of a Symptomatic Carotid Web: A Case Report.
有症状颈动脉嵴的组织病理学检查:一例报告
NMC Case Rep J. 2024 Mar 19;11:69-74. doi: 10.2176/jns-nmc.2023-0181. eCollection 2024.
4
Carotid webs: a review of pathophysiology, diagnostic findings, and treatment options.颈动脉窦:病理生理学、诊断结果及治疗选择的综述。
J Neurointerv Surg. 2024 Nov 22;16(12):1294-1298. doi: 10.1136/jnis-2023-021243.
5
New asymptomatic thrombosis caused by carotid web during the acute period of cerebral infarction.新发现的脑梗死急性期颈动脉壁引起的无症状性血栓形成。
BMC Neurol. 2023 Jul 12;23(1):264. doi: 10.1186/s12883-023-03316-1.
6
Interventional compared with medical management of symptomatic carotid web: A systematic review.症状性颈动脉窦部介入治疗与药物治疗的比较:系统评价。
J Stroke Cerebrovasc Dis. 2022 Oct;31(10):106682. doi: 10.1016/j.jstrokecerebrovasdis.2022.106682. Epub 2022 Aug 20.
7
Comparative analysis between 1-D, 2-D and 3-D carotid web quantification.1D、2D和3D颈动脉网量化的比较分析。
J Neurointerv Surg. 2023 Feb;15(2):153-156. doi: 10.1136/neurintsurg-2021-018192. Epub 2022 Feb 16.
8
Stroke Recurrence in First-Ever Symptomatic Carotid Web: A Cohort Study.首次有症状的颈动脉网患者的卒中复发:一项队列研究。
J Stroke. 2021 May;23(2):253-262. doi: 10.5853/jos.2020.05225. Epub 2021 May 31.
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JAMA Neurol. 2021 Jul 1;78(7):826-833. doi: 10.1001/jamaneurol.2021.1101.
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