Abraham Manoj T, Wilson John
Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, New York.
Facial Plast Surg. 2025 Apr;41(2):274-276. doi: 10.1055/a-2510-6807. Epub 2025 Jan 20.
Exosomes have emerged as a promising therapeutic frontier in facial plastic surgery. Preclinical studies have demonstrated their ability to modulate wound healing, skin rejuvenation, hair growth, and nerve regeneration. Early clinical evidence suggests potential benefits in enhancing recovery after laser resurfacing, treating acne scars, and promoting hair growth. Despite their potential, there are currently no exosome products that are FDA-approved for medical use, and they should be considered experimental until receiving regulatory approval and robust clinical validation. As research advances, exosomes may offer valuable tools for facial plastic surgeons to improve patient outcomes and expand regenerative medicine applications in facial aesthetics and reconstruction.
外泌体已成为面部整形手术中一个有前景的治疗前沿领域。临床前研究已证明它们具有调节伤口愈合、皮肤年轻化、毛发生长和神经再生的能力。早期临床证据表明，在激光换肤后促进恢复、治疗痤疮瘢痕和促进毛发生长方面有潜在益处。尽管它们具有潜力，但目前尚无获得美国食品药品监督管理局（FDA）批准用于医疗用途的外泌体产品，在获得监管批准和充分的临床验证之前，它们应被视为实验性产品。随着研究的进展，外泌体可能为面部整形外科医生提供有价值的工具，以改善患者预后，并扩大再生医学在面部美学和重建中的应用。
