Edrees Wadhah Hassan, Al-Shehari Wadee Abdullah
Medical Microbiology Department, Faculty of Applied Sciences, Hajjah University, Hajjah, Yemen.
Medical Laboratory Department, Faculty of Medical Sciences, Al-Razi University, Sana'a, Yemen.
BMC Public Health. 2025 Jan 20;25(1):239. doi: 10.1186/s12889-025-21466-4.
Malaria is one of the important diseases that threatens the global health system, especially in developing countries, including Yemen. Based on surveillance data, this analysis aimed to assess the trend of malaria in Yemen over the last sixteen years from 2006 to 2021.
A retrospective analysis was conducted on secondary malaria data from the database from the Ministry of Public Health and Population in Yemen.
Of the 15,153,763 suspected cases, approximately 3,651,508 malaria cases were confirmed by both laboratory and clinical diagnoses. Plasmodium falciparum, P. vivax, mixed infections, P. malariae, and P. ovale were recorded at 1,118,117 (98.72%), 123,28 (1.10%), 1838 (0.16%), 155 (0.01%), and 30 (0.01%), respectively. Approximately 77.2% of all malaria cases were recorded in six governorates. Al Hudaydah recorded the highest number of malaria cases (1,231,294), followed by Hajjah (623,937), Taiz (450,051), Dhamar (167,399), Sa'adah (157,881), and Al-Mahweet (154,763). The overall incidence rate of malaria cases and P. falciparum, respectively, was 8.9 and 2.66 per 1,000 people. The highest mean incidence rate of malaria was recorded in Al Hudaydah, Hajjah, Al-Mahweet, Sa'adah, and Abyan, respectively, at 29.71, 19.49, 14.98, 10.62, and 10.14 per 1,000 people. Yemen reported 704 (0.02%) malaria death cases with an overall rate of case fatality of 0.03% and a mortality rate of 0.18 per 100,000 populations. The trend of case fatality decreased from 0.029% in 2006 to 0.015% in 2020, while the mortality rate per 100,000 individuals decreased from 0.3 in 2006 to 0.08 in 2021.
It currently suggests a continuous increase in the malaria burden without specifying trends or fluctuations and is becoming a public health threat and causing widespread concern. Therefore, the treatment and prevention of malaria infection are crucial for reducing mortality and complications by increasing the use of vector control tools and promoting early diagnosis and treatment.
疟疾是威胁全球卫生系统的重要疾病之一，在包括也门在内的发展中国家尤为如此。基于监测数据，本分析旨在评估2006年至2021年过去十六年也门疟疾的趋势。
对也门公共卫生和人口部数据库中的二次疟疾数据进行回顾性分析。
在15153763例疑似病例中，约3651508例经实验室和临床诊断确诊为疟疾病例。恶性疟原虫、间日疟原虫、混合感染、三日疟原虫和卵形疟原虫的记录分别为1118117例（98.72%）、12328例（1.10%）、1838例（0.16%）、155例（0.01%）和30例（0.01%）。所有疟疾病例中约77.2%记录在六个省份。荷台达省疟疾病例数最多（1231294例），其次是哈杰省（623937例）、塔伊兹省（450051例）、达玛尔省（167399例）、萨达省（157881例）和迈赫维特省（154763例）。疟疾病例和恶性疟原虫的总体发病率分别为每1000人8.9例和2.66例。疟疾平均发病率最高的分别是荷台达省、哈杰省、迈赫维特省、萨达省和阿比扬省，分别为每1000人29.71例、19.49例、14.98例、10.62例和10.14例。也门报告了704例（0.02%）疟疾死亡病例，总体病死率为0.03%，死亡率为每10万人口0.18例。病死率趋势从2006年的0.029%降至2020年的0.015%，而每10万人口的死亡率从2006年的0.3降至2021年的0.08。
目前表明疟疾负担持续增加，但未明确趋势或波动情况，正成为公共卫生威胁并引起广泛关注。因此，通过增加病媒控制工具的使用以及促进早期诊断和治疗来治疗和预防疟疾感染对于降低死亡率和并发症至关重要。
