N James Jeffrey, Bloomquist Ryan, Brown Kiara, Looney Stephen, Walker Dylan, Day Tyler
Louisiana State University Health New Orleans, LSUHSC School of Dentistry, 1100 Florida Avenue, New Orleans, LA, 70119, USA.
Dental College of Georgia, Augusta University, Augusta, GA, 30904, Georgia.
BMC Oral Health. 2025 Jan 20;25(1):108. doi: 10.1186/s12903-024-05300-8.
The purpose of this study was to determine if there were correlations between the length of time from hospital admission to surgical intervention and the frequency of complications in patients with odontogenic infections. While odontogenic infection is well studied in terms of interventions and outcomes, less is known about hospital utilization and resource burden of odontogenic infection with respect to timeliness to intervention. A retrospective cohort analysis was used to examine correlations between time from admission to surgical intervention and clinical outcomes. Patients included in this study were divided into three categories of length of time to the operating room: 0-12 h, 12.1-24 h, and greater than 24 h. Time of admission, time of surgical intervention, patient demographics, admission lab values, and space involvement were measured and compared to the primary outcome variables including complications of intubation attempts and type, ICU admission, length of hospitalization, number of changes in antibiotic therapy, and frequency of return to the operating room. We found that the length of time to the OR had a statistically significant association with length of hospital stay (p = 0.003) and number of changes in antibiotic therapy (p = 0.033). While overall length of hospital stay is inherently dependent on length of time to the OR, this relationship highlights the importance of timeliness to definitive intervention in order to reduce hospital burden. This study provides evidence on how to prioritize odontogenic infections in a hospital setting. We recommend treating odontogenic infection in less than 24 h from the time of admission in order to reduce costs and improve outcomes for patients.
本研究的目的是确定牙源性感染患者从入院到手术干预的时间长度与并发症发生频率之间是否存在相关性。虽然牙源性感染在干预措施和治疗结果方面已有充分研究，但对于牙源性感染在干预及时性方面的医院利用情况和资源负担却知之甚少。本研究采用回顾性队列分析来检验从入院到手术干预的时间与临床结果之间的相关性。本研究纳入的患者根据进入手术室的时间长度分为三类：0 - 12小时、12.1 - 24小时和大于24小时。记录入院时间、手术干预时间、患者人口统计学数据、入院实验室检查值以及病变累及范围，并与主要结局变量进行比较，这些变量包括插管尝试的并发症及类型、入住重症监护病房（ICU）情况、住院时间、抗生素治疗方案的更改次数以及返回手术室的频率。我们发现，到手术室的时间长度与住院时间（p = 0.003）和抗生素治疗方案的更改次数（p = 0.033）存在统计学上的显著关联。虽然总体住院时间本质上取决于到手术室的时间长度，但这种关系凸显了及时进行确定性干预对于减轻医院负担的重要性。本研究为在医院环境中如何对牙源性感染进行优先排序提供了依据。我们建议在入院后24小时内治疗牙源性感染，以降低成本并改善患者的治疗效果。
