Zhuang Jinyang, Lei Xiyuan, Guo Xiaoli, Ding Li, Jia Jie
Department of Rehabilitation Medicine, Shanghai Jing'an District Central Hospital, Shanghai, China.
School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Clin Neurophysiol Pract. 2024 Dec 15;10:12-21. doi: 10.1016/j.cnp.2024.12.004. eCollection 2025.
To elucidate the immediate electrophysiological effects of mirror visual feedback (MVF) combined with or without touch task in subacute stroke.
Subacute stroke patients and healthy controls were recruited to participate in four grasping tasks (MVF or no MVF, combined with rubber ball or no ball) under electroencephalogram (EEG) monitoring. Event-related desynchronization (ERD) /event-related synchronization (ERS) and the lateralization index (LI) were utilized to observe the electrophysiological effects.
MVF reduced ERD suppression in the contralateral primary motor cortex (M1) of stroke patients. This reduction was observed in the low mu band for the contralateral parietal cortex during pure MVF. The laterality effects in the low mu band under MVF was noted in M1 for stroke patients and in the parietal cortex for all participants.
MVF inhibits the excitability of the contralateral M1 for subacute stroke. MVF inhibit activities in the contralateral M1 and parietal cortex, and reestablished hemispheric balance in the low mu band.
MVF has an instantaneous effect on subacute stroke by inhibiting the excitability of the contralateral sensorimotor cortex. The attenuated ERD in the low mu band in contralateral M1 and parietal cortex may serve as biomarkers of MVF for stroke rehabilitation.
阐明镜像视觉反馈（MVF）结合或不结合触摸任务对亚急性卒中的即时电生理效应。
招募亚急性卒中患者和健康对照，在脑电图（EEG）监测下参与四项抓握任务（MVF或无MVF，结合橡胶球或无球）。利用事件相关去同步化（ERD）/事件相关同步化（ERS）和偏侧化指数（LI）观察电生理效应。
MVF降低了卒中患者对侧初级运动皮层（M1）的ERD抑制。在单纯MVF期间，对侧顶叶皮层的低μ频段观察到这种降低。在MVF下，低μ频段的偏侧化效应在卒中患者的M1中以及所有参与者的顶叶皮层中均有记录。
MVF抑制亚急性卒中对侧M1的兴奋性。MVF抑制对侧M1和顶叶皮层的活动，并在低μ频段重新建立半球平衡。
MVF通过抑制对侧感觉运动皮层的兴奋性对亚急性卒中产生即时效应。对侧M1和顶叶皮层低μ频段ERD的减弱可能作为MVF用于卒中康复的生物标志物。
