School of Physical Education, Physiotherapy and Occupational Therapy, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
School of Kinesiology, Auburn University, Auburn, USA.
Brain Res Bull. 2021 Dec;177:217-238. doi: 10.1016/j.brainresbull.2021.10.003. Epub 2021 Oct 7.
Available literature indicates that 30-66% of stroke survivors present persistent upper limb impairment. Considering the importance of upper limb function for activities of daily living, it is necessary to investigate neurorehabilitation therapies that could improve the upper limb function. Among stroke complementary therapies, mirror therapy has shown promising results. Thus, the aim of this systematic review and meta-analyses was to review and synthesize clinical evidence on the use of mirror therapy on motor recovery of the upper limb and activities of daily living, and its neural correlates in stroke patients. The literature search was carried out in PubMed, ISI Web of Science, and Scopus databases. Twenty-nine studies met all the inclusion criteria. Two meta-analyses were conducted to compare mirror therapy with sham therapy on two general measures, upper limb assessment and activities of daily living. Results suggest that mirror therapy was better than sham therapy, mainly in the subacute phase, but the meta-analyses were nonsignificant. In addition, mirror therapy and cortical reorganization showed potential neural correlates, such as the primary motor cortex, precuneus, and posterior cingulate cortex.
现有文献表明，30-66%的中风幸存者存在持续性上肢功能障碍。考虑到上肢功能对日常生活活动的重要性，有必要研究能够改善上肢功能的神经康复治疗方法。在中风的补充疗法中，镜像疗法显示出了很有前景的结果。因此，本系统综述和荟萃分析的目的是回顾和综合镜像疗法在中风患者上肢运动功能恢复和日常生活活动及其神经相关性方面的临床证据。文献检索在 PubMed、ISI Web of Science 和 Scopus 数据库中进行。有 29 项研究符合所有纳入标准。进行了两项荟萃分析，以比较镜像疗法与假镜疗法在两项常规测量指标上的效果，即上肢评估和日常生活活动。结果表明，镜像疗法优于假镜疗法，主要是在亚急性期，但荟萃分析没有统计学意义。此外，镜像疗法和皮质重组显示出潜在的神经相关性，例如初级运动皮层、楔前叶和后扣带回皮层。
