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肝移植的碳足迹与能源消耗

The carbon footprint and energy consumption of liver transplantation.

作者信息

De Simone Paolo, Lai Quirino, Ducci Juri, Campani Daniela, Biancofiore Giandomenico

机构信息

Liver Transplant Program University of Pisa Medical School Hospital, Pisa, Italy.

Department of Surgical, Medical, Biomolecular Pathology and Intensive Care, University of Pisa, Pisa, Italy.

出版信息

Front Transplant. 2025 Jan 6;3:1441928. doi: 10.3389/frtra.2024.1441928. eCollection 2024.

Abstract

BACKGROUND AND AIMS

There is growing interest in the environmental impact of surgical procedures, yet more information is needed specifically regarding liver transplantation. This study aims to quantify the total greenhouse gas emissions, or carbon footprint, associated with adult whole-size liver transplantation from donors after brain death, including the relevant back-table graft preparation.

METHODS

The carbon footprint was calculated retrospectively using a bottom-up approach. This approach sums the volumes of energy consumption (kWh), volatile anesthetics (ml), solid waste (kg), and units of blood products transfused for each transplant. These consumption values were converted using validated conversion factors to the equivalent mass of carbon dioxide released into the environment (kg CO2e).

RESULTS

A total of 147 patients with a mean age of 55 years (male, 78.9%) who underwent liver transplants between 2021 and 2022 were analyzed, resulting in 45.5 tons CO2e. The mean (SD) carbon footprint for each procedure was 309.8 (33.2) kg CO2e [95% CI: 304.4; 315.3]. Total energy power consumption was 96.5 MW, contributing 65.4% of greenhouse emissions (29.8 tons CO2e), while volatile anesthetics, solid waste, and blood product transfusions contributed 8.0% (3.64 tons CO2e), 5.9% (2.7 tons CO2e), and 20.6% (9.4 tons CO2e), respectively. The duration of surgery ( = 29.0;  < 0.001), transfused red blood cells ( = 13.1;  < 0.001), fresh frozen plasma ( = 11.1;  < 0.001), platelets ( = 8.9;  < 0.001), and the use of an extracorporeal pump machine ( = 3.6;  < 0.001) had the greatest effects on greenhouse gas emissions.

CONCLUSIONS

Liver transplantation requires significant energy and is associated with considerable greenhouse gas emissions, particularly during longer procedures. Transplant clinicians, hospital administrators, policymakers, and patients should be aware of the environmental impact of liver transplantation and collaborate to adopt sustainable energy practices.

摘要

背景与目的

人们对外科手术的环境影响越来越感兴趣,但关于肝移植还需要更多具体信息。本研究旨在量化与脑死亡后供体的成人全尺寸肝移植相关的温室气体总排放量,即碳足迹,包括相关的手术台上移植物制备。

方法

采用自下而上的方法回顾性计算碳足迹。该方法汇总了每次移植的能源消耗(千瓦时)、挥发性麻醉剂(毫升)、固体废物(千克)以及输注的血液制品单位数量。这些消耗值使用经过验证的转换因子转换为释放到环境中的二氧化碳当量质量(千克二氧化碳当量)。

结果

对2021年至2022年间接受肝移植的147例平均年龄55岁(男性占78.9%)患者进行了分析,结果显示碳足迹为45.5吨二氧化碳当量。每次手术的平均(标准差)碳足迹为309.8(33.2)千克二氧化碳当量[95%置信区间:304.4;315.3]。总能源消耗为96.5兆瓦,占温室气体排放量的65.4%(29.8吨二氧化碳当量),而挥发性麻醉剂、固体废物和血液制品输注分别占8.0%(3.64吨二氧化碳当量)、5.9%(2.7吨二氧化碳当量)和20.6%(9.4吨二氧化碳当量)。手术时长(=29.0;<0.001)、输注的红细胞(=13.1;<0.001)、新鲜冰冻血浆(=11.1;<0.001)、血小板(=8.9;<0.001)以及体外泵的使用(=3.6;<0.001)对温室气体排放影响最大。

结论

肝移植需要大量能源,并且与相当多的温室气体排放相关,尤其是在较长的手术过程中。移植临床医生、医院管理人员、政策制定者和患者应意识到肝移植的环境影响,并共同采取可持续能源实践。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a4/11743657/a7cffba95f31/frtra-03-1441928-g001.jpg

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