Schmidt B, Luger A
Hautarzt. 1979 Dec;30(12):662-5.
Sources of error in the detection of specific IgM-antibodies against Treponema pallidum could be overcome by the introduction of a new method for precise separation of immunoglobulins. The 19-S-IgM-FTA-ABS-test apparently permits a correct diagnosis of syphilitic reinfection. This method is not only specific but also earlier reactive than the VDRL-test. The short-time persistence of 19 S-IgM production after treatment and its renewed appearance enables for the first time a differentiation between treatment failure and reinfection.
通过引入一种精确分离免疫球蛋白的新方法,可以克服检测梅毒螺旋体特异性 IgM 抗体时的误差来源。19-S-IgM-FTA-ABS 试验显然可以正确诊断梅毒再感染。该方法不仅具有特异性,而且比 VDRL 试验更早出现反应。治疗后 19 S-IgM 产生的短暂持续及其再次出现首次使得能够区分治疗失败和再感染。