Kim Sunghyun, Kwon Yoonsung, Lee Jong Yeon
Onnuri Eye Hospital, Jeollabuk-do, South Korea.
Department of Ophthalmology, College of Medicine Gil Medical Center, Gachon University, Incheon, South Korea.
Sci Rep. 2025 Jan 21;15(1):2738. doi: 10.1038/s41598-025-87222-1.
The purpose of this study was to evaluate the difference in the incidence of the hypertensive phase (HP) between Ahmed glaucoma valve (AGV) patients who received intracameral air injection and those who did not. A total of 78 patients who underwent AGV surgery between January 1, 2016 and June 30, 2023 were included in this retrospective study. HP was defined as intraocular pressure (IOP) greater than 21 mmHg within the first 6 postoperative months. Among baseline characteristics, except for neovascular glaucoma and baseline IOP, there were no differences between the air injection and control groups. In the air injection group, the rate of HP was 19%, which was significantly lower than 49.1% in the control group (p = 0.017). In multivariate logistic regression analysis, baseline IOP had a significant positive correlation (OR: 1.120, p = 0.026), while age and intracameral air injection had a significant negative correlation with the incidence of HP (OR: 0.938, p = 0.028, OR: 0.142, p = 0.029). Postoperative IOP at 1 year and surgical success rates were not different between the two groups. Intracameral air injection during AGV surgery can significantly reduce the risk of HP. Intracameral air injection can be a simple procedure in AGV surgery for reducing HP.
本研究的目的是评估接受前房内空气注射的艾哈迈德青光眼引流阀（AGV）患者与未接受该注射的患者之间高血压期（HP）发生率的差异。本回顾性研究纳入了2016年1月1日至2023年6月30日期间接受AGV手术的78例患者。HP定义为术后6个月内眼压（IOP）大于21 mmHg。在基线特征方面，除新生血管性青光眼和基线眼压外，空气注射组和对照组之间无差异。空气注射组的HP发生率为19%，显著低于对照组的49.1%（p = 0.017）。在多因素逻辑回归分析中，基线眼压具有显著正相关性（OR：1.120，p = 0.026），而年龄和前房内空气注射与HP发生率具有显著负相关性（OR：0.938，p = 0.028，OR：0.142，p = 0.029）。两组术后1年的眼压和手术成功率无差异。AGV手术期间前房内空气注射可显著降低HP风险。前房内空气注射在AGV手术中可能是一种降低HP的简单操作。
