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伴有明显单侧小脑幕硬脑膜炎的慢性脑膜炎

Chronic meningitis with marked unilateral tentorial pachymeningitis.

作者信息

Kobayashi N, Hongo K, Kawauchi M, Kobayashi S, Sugita K

出版信息

Surg Neurol. 1985 May;23(5):529-35. doi: 10.1016/0090-3019(85)90251-4.

Abstract

Two cases of chronic meningitis with marked granulomatous thickening of the cerebellar tentorium are presented. The clinical features of both cases were those of chronic meningitis, namely, incessant chronic headache, long-lasting moderate increase of intracranial pressure, multiple cranial nerve involvement, slight lymphocytosis, and increased protein in cerebrospinal fluid. The characteristic finding on computed tomography scan was slight, high density of the unilateral cerebellar tentorium with marked contrast enhancement. Both patients died of complications, and necropsy revealed marked granulomatous thickening of the unilateral cerebellar tentorium. Although noninfectious disease was strongly suspected, the etiology could not be specified either clinically or by necropsy.

摘要

本文报告两例慢性脑膜炎患者,其小脑幕出现明显的肉芽肿性增厚。两例患者的临床特征均符合慢性脑膜炎,即持续性慢性头痛、颅内压长期中度升高、多组颅神经受累、轻度淋巴细胞增多以及脑脊液中蛋白质含量增加。计算机断层扫描的特征性表现为单侧小脑幕轻度高密度影,并伴有明显的对比增强。两名患者均死于并发症,尸检显示单侧小脑幕有明显的肉芽肿性增厚。尽管强烈怀疑为非感染性疾病,但临床及尸检均未能明确病因。

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