Moradi Golnaz, Etehadi Safa S, Mousavi Seyed H, Mohammadi Rayeheh
Department of Radiology, Sina Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences, Tehran, Iran.
J Community Hosp Intern Med Perspect. 2024 Nov 2;14(6):23-29. doi: 10.55729/2000-9666.1411. eCollection 2024.
It has been shown that cavitary lesions on CT scans of patients with COVID-19 may be related to their clinical symptoms and mortality rate.
The study population included patients diagnosed with COVID-19 based on RT-PCR results from throat samples or typical clinical and chest CT scan findings who were hospitalized at Sina Hospital in Tehran in 2020 and underwent chest CT scans. Chest CT scans were examined for the severity of pulmonary opacities and the presence, number, size, wall thickness, and distribution of cavitary lung lesions.
Oxygen saturation was lower in patients with cavitary lesions in the initial state and after treatment than those without cavitation, and a statistically significant relationship was observed (p < 0.05). In terms of gender, a significant correlation was observed, and the prevalence of cavitary lesions was higher in men (p < 0.05). Also, the in-hospital mortality rate was higher in patients with cavitary lesions (p < 0.05).
Based on our results, the presence of cavitary lung lesions in COVID-19 patients is related to the mortality rate, severity of pulmonary involvement, and patients' gender.
研究表明，新型冠状病毒肺炎（COVID-19）患者CT扫描中的空洞性病变可能与其临床症状和死亡率有关。
研究人群包括2020年在德黑兰的西娜医院住院并接受胸部CT扫描的患者，这些患者根据咽喉样本的逆转录聚合酶链反应（RT-PCR）结果或典型的临床及胸部CT扫描结果被诊断为COVID-19。对胸部CT扫描结果进行检查，以评估肺部混浊的严重程度以及空洞性肺病变的存在情况、数量、大小、壁厚和分布。
有空洞性病变的患者在初始状态及治疗后的血氧饱和度低于无空洞的患者，差异具有统计学意义（p < 0.05）。在性别方面，观察到显著相关性，男性空洞性病变的患病率更高（p < 0.05）。此外，有空洞性病变的患者院内死亡率更高（p < 0.05）。
根据我们的研究结果，COVID-19患者肺部空洞性病变的存在与死亡率、肺部受累的严重程度以及患者性别有关。
