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当代及新出现的因素对违法青年男性血铅浓度的影响:来自一个中等收入国家的案例研究

The influence of contemporary and emerging factors on blood lead concentrations among young males in conflict with the law: a case study from a middle-income country.

作者信息

Mbonane Thokozani P, Swart Andre, Mathee Angela, Naicker Nisha

机构信息

Department of Environmental Health, Faculty of Health Sciences, University of Johannesburg, Johannesburg, South Africa.

Environment and Health Research Unit, South African Medical Research Council, Johannesburg, South Africa.

出版信息

Front Epidemiol. 2025 Jan 7;4:1425604. doi: 10.3389/fepid.2024.1425604. eCollection 2024.

DOI:10.3389/fepid.2024.1425604
PMID:39839809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11747412/
Abstract

INTRODUCTION

Scientific evidence shows that contemporary and emerging factors contribute to high blood lead concentrations in different populations. The study aimed to determine blood lead concentrations and risk factors associated with high blood lead concentrations among young males in conflict with the law.

METHODS

A cross-sectional analytical study was conducted among 192 conveniently selected participants from two youth secure (correctional) facilities in Gauteng Province, South Africa.

RESULTS

The study's overall blood lead concentration median was 3.30 μg/dl, ranging from 0.85 to 48.11 μg/dl. Young males born outside of South Africa (median = 8.78 μg/dl) and in villages (median = 4.95 μg/dl), working before coming to the facility (median = 5.23 μg/dl) and involvement in illegal mining (median = 9.00 μg/dl) had high blood lead concentrations in this study. Contemporary and emerging risk factors such as being born outside the country (AOR: 3.10, 95%CI: 1.01-1.88), involvement in illegal mining activities (AOR: 1.36, 95%CI: 1.14-1.91) and staying in a house with peeling paint on the outside (AOR: 2.26, 95%CI: 1.12-4.30) were found to influence blood lead concentration.

DISCUSSION

The study findings show that contemporary (co-existing) and emerging factors influence blood lead concentrations. Therefore, there is a need to investigate these factors further in communities that may be affected. Lastly, there is a need for a holistic approach involving multiple sectors to introduce human lead concentration screening and preventive programmes.

摘要

引言

科学证据表明,当代和新出现的因素导致不同人群血铅浓度升高。本研究旨在确定违法青年男性的血铅浓度以及与高血铅浓度相关的风险因素。

方法

对从南非豪登省两个青少年安全(教养)设施中方便选取的192名参与者进行了横断面分析研究。

结果

该研究的总体血铅浓度中位数为3.30μg/dl,范围为0.85至48.11μg/dl。在本研究中,出生在南非境外(中位数=8.78μg/dl)和农村(中位数=4.95μg/dl)、进入该设施之前有工作经历(中位数=5.23μg/dl)以及参与非法采矿(中位数=9.00μg/dl)的青年男性血铅浓度较高。研究发现,诸如出生在国外(比值比:3.10,95%置信区间:1.01-1.88)、参与非法采矿活动(比值比:1.36,95%置信区间:1.14-1.91)以及居住在外部有油漆剥落的房屋中(比值比:2.26,95%置信区间:1.12-4.30)等当代和新出现的风险因素会影响血铅浓度。

讨论

研究结果表明,当代(并存)和新出现的因素会影响血铅浓度。因此,有必要在可能受影响的社区进一步调查这些因素。最后,需要采取涉及多个部门的整体方法来推行人体铅浓度筛查和预防方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63de/11747412/dd59a84dd417/fepid-04-1425604-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63de/11747412/48dec999fa2d/fepid-04-1425604-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63de/11747412/6879c44af9a4/fepid-04-1425604-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63de/11747412/dd59a84dd417/fepid-04-1425604-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63de/11747412/48dec999fa2d/fepid-04-1425604-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63de/11747412/6879c44af9a4/fepid-04-1425604-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63de/11747412/dd59a84dd417/fepid-04-1425604-g003.jpg

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Lancet Planet Health. 2023 Oct;7(10):e831-e840. doi: 10.1016/S2542-5196(23)00166-3. Epub 2023 Sep 12.
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尼日利亚奥孙州一个金矿社区儿童的血铅含量过高:紧急呼吁采取行动。
Trans R Soc Trop Med Hyg. 2023 Oct 3;117(10):714-726. doi: 10.1093/trstmh/trad035.
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Hypertens Res. 2023 Feb;46(2):395-407. doi: 10.1038/s41440-022-01069-x. Epub 2022 Oct 18.
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