Al Ghadeer Hussain A, Mohamed Ahad A, Alali Mariam A, Al Mahdi Kulthum A, Almishal Sajeda M, Aljubran Tawfiq M, Alneamah Abdulelah A, Alduhmush Roaa S, Alobaid Mohammed J, Alsaad Tarfh S, Almoagal Hayam S, Albuali Abdullah M, Alsuliman Mudhawi F, Althafar Noor A, Al-Shaalan Essa F
Pediatrics, Maternity and Children Hospital, Al-Hofuf, SAU.
Pediatrics, Johns Hopkins Aramco Healthcare, Dhahran, SAU.
Cureus. 2024 Dec 21;16(12):e76137. doi: 10.7759/cureus.76137. eCollection 2024 Dec.
Background The incidence of pregnancy-associated diabetes has increased in recent decades, leading to neonatal adverse outcomes like metabolic and hematologic disorders, respiratory distress, cardiac disorders, and neurologic impairment. Macrosomia, a common consequence of diabetes, is influenced by maternal blood glucose levels, impacting adverse neonatal outcomes. Aim The current study aimed to assess the neonatal and maternal outcomes of the infants of diabetic mothers. Methods An observational retrospective study was conducted among infants of diabetic mothers at Maternity and Children Hospital, Saudi Arabia, from 2022 to 2023. The data included socio-demographic details, diabetes-related information, and maternal and neonatal outcomes. Results A study of 400 mothers aged 18-40 years found that 54.3% had 1-4 previous pregnancies, while 35.5% had more than four. The majority had gestational diabetes mellitus (GDM), with 25.5% having diabetes for more than five years. The most common complications were preeclampsia (7.5%), polyhydramnios (6%), UTI (5.3%), PROM (4.3%), and pregnancy-induced hypertension (4.3%). The majority had no complications, while 12.5% of neonates had respiratory and metabolic complications. Conclusion The study found that most women with gestational diabetes had previously been diagnosed with diabetes mellitus (DM) and are multiparous, with Caesarean delivery being the dominant mode. While maternal complications were seen in only less than one-third of mothers, neonatal complications were noted in 12.5%.
近几十年来,妊娠相关糖尿病的发病率有所上升,导致新生儿出现代谢和血液系统疾病、呼吸窘迫、心脏疾病和神经功能障碍等不良后果。巨大儿是糖尿病的常见后果,受母体血糖水平影响,会影响新生儿不良结局。
本研究旨在评估糖尿病母亲所生婴儿的新生儿和母亲结局。
2022年至2023年在沙特阿拉伯妇幼医院对糖尿病母亲所生婴儿进行了一项观察性回顾性研究。数据包括社会人口学细节、糖尿病相关信息以及母亲和新生儿结局。
对400名年龄在18至40岁之间的母亲进行的研究发现,54.3%的母亲既往有1至4次妊娠,而35.5%的母亲有超过4次妊娠。大多数患有妊娠期糖尿病(GDM),25.5%的母亲患有糖尿病超过5年。最常见的并发症是子痫前期(7.5%)、羊水过多(6%)、尿路感染(5.3%)、胎膜早破(4.3%)和妊娠高血压(4.3%)。大多数母亲无并发症,而12.5%的新生儿有呼吸和代谢并发症。
研究发现,大多数妊娠期糖尿病女性既往被诊断为糖尿病(DM)且为经产妇,剖宫产为主要分娩方式。虽然只有不到三分之一的母亲出现母体并发症,但12.5%的新生儿出现了并发症。