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分析一组妊娠期糖尿病患者的母婴并发症。

Analysis of Maternal and Neonatal Complications in a Group of Patients with Gestational Diabetes Mellitus.

机构信息

Department of Obstetrics and Ginecology, Clinical County Emergency Hospital, 200349 Craiova, Romania.

Department of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.

出版信息

Medicina (Kaunas). 2021 Oct 28;57(11):1170. doi: 10.3390/medicina57111170.

Abstract

: Gestational diabetes mellitus (GDM) represents one of the most common complications during pregnancy, being associated with numerous maternal and neonatal complications. The study aimed to analyze maternal and neonatal complications associated with GDM. The risk factors of GDM and of the maternal and neonatal complications were studied in order to prevent their occurrence. : The study included 97 women in the study, who underwent an oral glucose tolerance test (OGTT) between weeks 24-28 of pregnancy, consequently being divided into two groups: pregnant women with and without GDM. Statistical analysis was performed using the SPSS 26.0 software and MATLAB fitglm, the results being considered statistically significant if < 0.05. : We observed statistically significant differences between the group of women with and without GDM, regarding gestational hypertension (17.6% vs. 0%), preeclampsia (13.72% vs. 0%), and cesarean delivery (96.1% vs. 78,3%). Data on the newborn and neonatal complications: statistically significant differences were recorded between the two groups (GDM vs. no GDM) regarding the average weight at birth (3339.41 ± 658.12 g vs. 3122.83 ± 173.67 g), presence of large for gestational age (21.6% vs. 0%), macrosomia (13.7% vs. 0%), excessive fetal growth (35.3% vs. 0%), respiratory distress (31.4% vs. 0%), hospitalization for at least 24 h in the Neonatal Intensive Care Unit (9.80% vs. 0%), and APGAR score <7 both 1 and 5 min following birth (7.8% vs. 0%). Additionally, the frequency of neonatal hypoglycemia and hyperbilirubinemia was higher among newborns from mothers with GDM. The screening and diagnosis of GDM is vital, and appropriate management is required for the prevention of maternal and neonatal complications associated with GDM. It is also important to know the risk factors for GDM and attempt to prevent their appearance.

摘要

妊娠期糖尿病(GDM)是妊娠期间最常见的并发症之一,与许多母婴并发症有关。本研究旨在分析与 GDM 相关的母婴并发症。研究了 GDM 及母婴并发症的危险因素,以预防其发生。

该研究纳入了 97 名在妊娠 24-28 周期间接受口服葡萄糖耐量试验(OGTT)的女性,随后将其分为两组:患有 GDM 和不患有 GDM 的孕妇。使用 SPSS 26.0 软件和 MATLAB fitglm 进行统计学分析,结果认为如果 <0.05,则具有统计学意义。

我们观察到患有和不患有 GDM 的两组女性之间存在统计学显著差异,包括妊娠期高血压(17.6% vs. 0%)、子痫前期(13.72% vs. 0%)和剖宫产(96.1% vs. 78.3%)。关于新生儿和新生儿并发症的数据:两组之间记录到统计学显著差异(GDM 与非 GDM),包括出生时的平均体重(3339.41 ± 658.12 g 与 3122.83 ± 173.67 g)、巨大儿的存在(21.6% vs. 0%)、巨大儿(13.7% vs. 0%)、胎儿过度生长(35.3% vs. 0%)、呼吸窘迫(31.4% vs. 0%)、至少在新生儿重症监护病房住院 24 小时(9.80% vs. 0%)和出生后 1 分钟和 5 分钟时的 APGAR 评分<7(7.8% vs. 0%)。此外,患有 GDM 的母亲所生新生儿的新生儿低血糖症和高胆红素血症的频率更高。

GDM 的筛查和诊断至关重要,需要进行适当的管理以预防与 GDM 相关的母婴并发症。了解 GDM 的危险因素并尝试预防其发生也很重要。

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