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多发性硬化症中视神经炎的非典型表现。

Atypical Presentation of Optic Neuritis in Multiple Sclerosis.

作者信息

Mukhtar Marwa, Naseer Mohib, Yasin Malik Mudasser, Luqman Faizan

机构信息

Ophthalmology, Medical Teaching Institution (MTI) Ayub Teaching Hospital, Abbottabad, PAK.

Ophthalmology, Medical Teaching Institution (MTI) Khyber Teaching Hospital, Peshawar, PAK.

出版信息

Cureus. 2024 Dec 21;16(12):e76169. doi: 10.7759/cureus.76169. eCollection 2024 Dec.

DOI:10.7759/cureus.76169
PMID:39840190
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11747543/
Abstract

Optic neuritis (ON) is the inflammation of the optic nerve. 'Typical' ON is commonly associated with multiple sclerosis (MS) and its classic triad includes sudden loss of vision, pain with eye movement and dyschromatopsia. It usually has good visual outcome irrespective of treatment. Presentation other than this is termed as 'atypical' ON and causes include autoimmune diseases, infections and optic neuropathy related to systemic disorders, etc. These cases of ON need specific treatment depending on the cause. Therefore, it is vital to differentiate 'typical' from 'atypical' ON. Here, we present a case of ON associated with MS, which presented with atypical symptoms i.e. painless loss of vision. Moreover, this patient had a poor final visual outcome, in contrast to the generally good visual prognosis of ON associated with MS.

摘要

视神经炎(ON)是视神经的炎症。“典型”视神经炎通常与多发性硬化症(MS)相关,其典型三联征包括视力突然丧失、眼球运动时疼痛和色觉障碍。无论是否接受治疗,其视力预后通常良好。除此之外的表现被称为“非典型”视神经炎,病因包括自身免疫性疾病、感染以及与全身性疾病相关的视神经病变等。这些视神经炎病例需要根据病因进行特殊治疗。因此,区分“典型”和“非典型”视神经炎至关重要。在此,我们报告一例与多发性硬化症相关的视神经炎病例,该病例表现为非典型症状,即无痛性视力丧失。此外,与通常视力预后良好的多发性硬化症相关性视神经炎相比,该患者最终视力预后较差。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9804/11747543/fcb8320ba8f6/cureus-0016-00000076169-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9804/11747543/ae3e9d01dcdf/cureus-0016-00000076169-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9804/11747543/fcb8320ba8f6/cureus-0016-00000076169-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9804/11747543/ae3e9d01dcdf/cureus-0016-00000076169-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9804/11747543/fcb8320ba8f6/cureus-0016-00000076169-i02.jpg

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本文引用的文献

1
Atypical optic neuritis: An overview.非典型性视神经炎:概述。
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2
Case for a new corticosteroid treatment trial in optic neuritis: review of updated evidence.视神经炎新皮质类固醇治疗试验的病例:最新证据综述
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Optic neuritis as an early sign of multiple sclerosis.视神经炎作为多发性硬化症的早期症状。
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The Diagnosis and Treatment of Optic Neuritis.视神经炎的诊断与治疗
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Treatment options for atypical optic neuritis.非典型视神经炎的治疗选择。
Indian J Ophthalmol. 2014 Oct;62(10):982-4. doi: 10.4103/0301-4738.145986.
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Optic neuritis, its differential diagnosis and management.视神经炎、其鉴别诊断及管理
Open Ophthalmol J. 2012;6:65-72. doi: 10.2174/1874364101206010065. Epub 2012 Jul 24.
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