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赞比亚利文斯通大学医院伤害致死的患病率。一项回顾性横断面研究。

Prevalence of mortality caused by injuries at Livingstone University Hospital, Zambia. A retrospective cross-sectional study.

作者信息

Siame Lukundo, Malumani Malan, Kaseya Chiyeñu O R, Ivashchenko Sergiy, Nombwende Leah, Masenga Sepiso K, Hamooya Benson M, Miyoba Michelo Haluuma

机构信息

School of Medicine and Health Sciences, Mulungushi University, Livingstone, Zambia.

Livingstone University Teaching Hospital, Livingstone, Zambia.

出版信息

PLoS One. 2025 Jan 22;20(1):e0314068. doi: 10.1371/journal.pone.0314068. eCollection 2025.

Abstract

BACKGROUND

Trauma is a major global public health issue, with an annual death toll of approximately 5 million, disproportionately affecting low- and middle-income countries. Zambia bears a significant burden of trauma-related mortalities, contributing to 7% of all annual deaths and 1 in 5 premature deaths in the country. Despite the significant burden of trauma in our country, few studies have been conducted, with most focusing on high-population centers, and there is a lack of epidemiological data on trauma-related deaths in our region. Therefore, our aim was to estimate the proportion of deaths caused by injuries at Livingstone University Teaching Hospital, a tertiary hospital located in Zambia's southern province.

METHODS

We conducted a retrospective cross-sectional study from June 22, 2020, to June 22, 2021, among 956 individuals from 1 month old (29 days of age) to 100 years. Demographic and clinical data were collected from patient's records from Accident and Emergency department. Data analysis included descriptive statistics, chi square, mann-whitney test and multivariable logistic using forward stepwise generalized linear model equations (GLM) to identified factors associated with mortality, with a significance level set at p < 0.05. Data were analyzed using STATA version 15.

RESULTS

Among the study participants, the median age was 26 years (interquartile range (IQR) 15, 37) and the majority were males (74.2%, n = 709). Prevalence of mortality was 1.0% (n = 10). The deaths were caused by burns (60%, n = 6), violence (30%, n = 3), and traffic accidents (10%, n = 1). Among those who died, the majority of the trauma occurred at home (90%, n = 9), followed by road (10%, n = 1) and were as a result of burns (60%, n = 6) and community violence (30%, n = 3). Survivors had significantly higher treatment costs (ZMK 9,837 vs. ZMK 6,037, p<0.005). Having burns (AOR: 1.06, 95% CI: 1.05, 1.09, p< 0.001) and hospital stay of one day (AOR: 1.04, 95% CI: 1.02, 1.05, p< 0.001) was positively associated with mortality, while hospital stay of more than five days (AOR: 0.98, 95% CI: 0.96, 0.99, p = 0.002) was negatively associated with mortality.

CONCLUSION

The prevalence of death due to trauma was relatively low, with the majority experiencing multiple traumas. Burns were the most common cause and were associated with death, occurring within a day of hospitalization. The findings underscore the need for targeted preventive measures, improved access to quality emergency trauma care, and rehabilitation services, especially among patients with burns.

摘要

背景

创伤是一个重大的全球公共卫生问题,每年造成约500万人死亡,对低收入和中等收入国家的影响尤为严重。赞比亚承受着与创伤相关的巨大死亡负担,占该国每年所有死亡人数的7%,每5例过早死亡中就有1例与之相关。尽管我国创伤负担沉重,但相关研究较少,大多数研究集中在人口密集的中心地区,且我们所在地区缺乏与创伤相关死亡的流行病学数据。因此,我们的目的是估计位于赞比亚南部省份的利文斯通大学教学医院因伤致死的比例。

方法

我们于2020年6月22日至2021年6月22日对956名年龄从1个月大(29天)到100岁的个体进行了一项回顾性横断面研究。从急诊科的患者记录中收集人口统计学和临床数据。数据分析包括描述性统计、卡方检验、曼-惠特尼检验以及使用向前逐步广义线性模型方程(GLM)的多变量逻辑回归,以确定与死亡率相关的因素,显著性水平设定为p<0.05。使用STATA 15版软件进行数据分析。

结果

在研究参与者中,年龄中位数为26岁(四分位间距(IQR)为15, 37),大多数为男性(74.2%,n = 709)。死亡率为1.0%(n = 10)。死亡原因包括烧伤(60%,n = 6)、暴力(30%,n = 3)和交通事故(10%,n = 1)。在死亡者中,大多数创伤发生在家中(90%,n = 9),其次是道路(10%,n = 1),主要原因是烧伤(60%,n = 6)和社区暴力(30%,n = 3)。幸存者的治疗费用显著更高(9837赞比亚克瓦查对6037赞比亚克瓦查,p<0.005)。烧伤(比值比:1.06,95%置信区间:1.05,1.09,p<0.001)和住院一天(比值比:1.04,95%置信区间:1.02,1.05,p<0.001)与死亡率呈正相关,而住院超过五天(比值比:0.98,95%置信区间:0.96,0.99,p = 0.002)与死亡率呈负相关。

结论

创伤导致的死亡率相对较低,大多数患者经历了多处创伤。烧伤是最常见的死因且与死亡相关,多发生在住院一天内。研究结果强调了采取针对性预防措施、改善获得优质紧急创伤护理和康复服务的必要性,尤其是对于烧伤患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0517/11753694/bc25488857fa/pone.0314068.g001.jpg

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