Torres Orlando Jorge Martins, Torzilli Guido, Enne Marcelo, Gonçalves Rinaldo, Santibanes Eduardo de, Pawlik Timothy, Adam Rene, Soubrane Olivier, Herman Paulo, Cotta-Pereira Ricardo Lemos
Hepatopancreatobiliary Surgery and Liver Transplant, Department of Gastrointestinal Surgery - São Luís (MA), Brazil.
IRCCS Humanitas Research Hospital, Division of Hepatobiliary and General Surgery - Rozzano, Milan, Italy.
Arq Bras Cir Dig. 2025 Jan 20;37:e1859. doi: 10.1590/0102-6720202400065e1859. eCollection 2025.
The development of surgical techniques, chemotherapy, biological agents, and multidisciplinary approaches have made patients with unresectable colorectal liver metastases eligible for surgery. Many strategies have been developed to allow patients for surgical resection (percutaneous portal vein embolization, liver venous deprivation, parenchyma-sparing liver surgery, reverse strategy, associating liver partition and portal vein ligation for staged hepatectomy, and liver transplantation), the only form of disease control and curative treatment.
手术技术、化疗、生物制剂以及多学科方法的发展，使无法切除的结直肠癌肝转移患者有了手术机会。目前已制定了多种策略以使患者能够接受手术切除（经皮门静脉栓塞、肝静脉阻断、保留肝实质的肝脏手术、逆向策略、联合肝脏分隔和门静脉结扎的分期肝切除术以及肝移植），而手术切除是疾病控制和根治性治疗的唯一形式。
