Bunge R, Glaser L, Lieberman M, Raben D, Salzer J, Whittenberger B, Woolsey T
J Supramol Struct. 1979;11(2):175-87. doi: 10.1002/jss.400110207.
Control of cell growth by cell to cell contact is reviewed with particular emphasis on two systems--contact inhibition of growth observed with Swiss 3T3 cells and the mitogenic stimulation of Schwann cells by dorsal root ganglia neurites. In both cases the biological effect can be reproduced by the addition of surface membranes to the corresponding cells. In the case of contact inhibition of 3T3 cells, biological activity appears to correlate with membrane binding to the cells. An octylglucoside extract of 3T3 plasma membranes retains the biological activity (growth inhibition) of the original membranes.
本文综述了细胞间接触对细胞生长的控制，特别强调了两个系统——瑞士3T3细胞中观察到的生长接触抑制，以及背根神经节神经突对雪旺细胞的促有丝分裂刺激。在这两种情况下，通过向相应细胞添加表面膜都可以重现生物学效应。就3T3细胞的接触抑制而言，生物学活性似乎与膜与细胞的结合相关。3T3质膜的辛基葡糖苷提取物保留了原始膜的生物学活性（生长抑制）。
