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精准康复的现状如何?一项带有咨询阶段的范围界定研究方案。

What is the current state of precision rehabilitation? Protocol for a scoping study with a consultation phase.

作者信息

Pouliot-Laforte Annie, Dubé Evemie, Kairy Dahlia, Levac Danielle E

机构信息

Department of Physical Activity Sciences, Faculté des sciences, Université du Québec à Montréal, Montreal, Quebec, Canada

Azrieli Research Center UHC Sainte-Justine, Montreal, Quebec, Canada.

出版信息

BMJ Open. 2025 Jan 21;15(1):e094119. doi: 10.1136/bmjopen-2024-094119.

DOI:10.1136/bmjopen-2024-094119
PMID:39842913
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11751979/
Abstract

INTRODUCTION

Precision health can be described as the right intervention, at the right time, for the right person, with a focus on monitoring and maintaining health in a longitudinal approach. Despite an increasing focus on precision approaches in medicine, their application in a rehabilitation context remains unexplored. As such, a greater understanding of the current state of the literature is required, in combination with clinician, researcher and healthcare manager perspectives regarding barriers and facilitators to the practical implementation of precision rehabilitation in clinical practice.

OBJECTIVE

Describe and map the current state of knowledge regarding precision rehabilitation to identify gaps in knowledge and inform future research directions and clinical implementation strategies.

METHODS AND ANALYSIS

A scoping study will be conducted following current methodological recommendations (Peters , 2021) and reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses-Scoping Review Extension guidelines. A convergent mixed-methods design will combine quantitative and qualitative findings. A search in Medline, CINAHL, Embase, Scopus, Web of Science and PsycINFO databases will be conducted for articles published between 2010 and 2023 referring to the concept of precision rehabilitation. Two reviewers will complete an abstract and full-text review based on eligibility criteria; data will be extracted from accepted papers using a data extraction framework. Results will be aggregated and synthesised using descriptive and thematic analyses. The consultation phase will involve a purposeful sampling of key stakeholders (clinicians, researchers and managers) in large North American rehabilitation centres. Semi-structured individual interviews will be conducted and analysed using deductive thematic analysis. Convergent mixed-methods data analyses will combine quantitative and qualitative datasets to highlight similarities and differences between the current literature on the subject and the understanding of stakeholders.

ETHICS AND DISSEMINATION

Ethical approval has been obtained from the Research Ethics Board of the Sainte-Justine University Health Centre (no. 2024-6324). Results will be disseminated through professional networks, conference presentations and publications in scientific journals.

摘要

引言

精准健康可被描述为在正确的时间,针对正确的人进行正确的干预,重点是以纵向方式监测和维持健康。尽管医学领域对精准方法的关注日益增加,但其在康复背景下的应用仍未得到探索。因此,需要更深入地了解当前文献的现状,并结合临床医生、研究人员和医疗保健管理人员对于精准康复在临床实践中实际应用的障碍和促进因素的看法。

目的

描述并梳理关于精准康复的现有知识状态,以识别知识空白,并为未来的研究方向和临床实施策略提供信息。

方法与分析

将按照当前的方法学建议(彼得斯等人,2021年)进行一项范围综述研究,并根据系统评价和Meta分析扩展版的首选报告项目指南进行报告。采用收敛性混合方法设计,将定量和定性研究结果相结合。将在Medline、CINAHL、Embase、Scopus、科学引文索引和PsycINFO数据库中检索2010年至2023年期间发表的提及精准康复概念的文章。两名评审员将根据纳入标准完成摘要和全文评审;将使用数据提取框架从入选论文中提取数据。结果将通过描述性分析和主题分析进行汇总和综合。咨询阶段将涉及对北美大型康复中心的关键利益相关者(临床医生、研究人员和管理人员)进行有目的的抽样。将进行半结构化的个人访谈,并采用演绎主题分析进行分析。收敛性混合方法数据分析将结合定量和定性数据集突出该主题当前文献与利益相关者理解之间的异同。

伦理与传播

已获得圣贾斯汀大学健康中心研究伦理委员会的伦理批准(编号2024 - 6324)。研究结果将通过专业网络、会议报告和科学期刊发表进行传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1e1/11751979/ddacaca7c974/bmjopen-15-1-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1e1/11751979/6dc50c9ac28a/bmjopen-15-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1e1/11751979/ddacaca7c974/bmjopen-15-1-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1e1/11751979/6dc50c9ac28a/bmjopen-15-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1e1/11751979/ddacaca7c974/bmjopen-15-1-g002.jpg

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本文引用的文献

1
Stepping Closer to Precision Rehabilitation.迈向精准康复
JAMA Neurol. 2023 Apr 1;80(4):339-341. doi: 10.1001/jamaneurol.2023.0044.
2
Arksey and O'Malley's consultation exercise in scoping reviews: A critical review.阿特金和奥马利的范围综述咨询实践:批判性评价。
J Adv Nurs. 2022 Aug;78(8):2304-2312. doi: 10.1111/jan.15265. Epub 2022 Apr 22.
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Precision Rehabilitation: Optimizing Function, Adding Value to Health Care.精准康复:优化功能,为医疗保健增值。
Arch Phys Med Rehabil. 2022 Jun;103(6):1233-1239. doi: 10.1016/j.apmr.2022.01.154. Epub 2022 Feb 15.
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Trends and gaps in precision health research: a scoping review.精准健康研究的趋势和差距:范围综述。
BMJ Open. 2021 Oct 25;11(10):e056938. doi: 10.1136/bmjopen-2021-056938.
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Updated methodological guidance for the conduct of scoping reviews.范围综述实施的更新方法学指南。
JBI Evid Synth. 2020 Oct;18(10):2119-2126. doi: 10.11124/JBIES-20-00167.
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Precision Medicine, AI, and the Future of Personalized Health Care.精准医学、人工智能与个性化医疗的未来
Clin Transl Sci. 2021 Jan;14(1):86-93. doi: 10.1111/cts.12884. Epub 2020 Oct 12.
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PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation.PRISMA 扩展用于范围审查 (PRISMA-ScR): 清单和解释。
Ann Intern Med. 2018 Oct 2;169(7):467-473. doi: 10.7326/M18-0850. Epub 2018 Sep 4.
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Toward achieving precision health.迈向精准健康。
Sci Transl Med. 2018 Feb 28;10(430). doi: 10.1126/scitranslmed.aao3612.
9
Code Saturation Versus Meaning Saturation: How Many Interviews Are Enough?代码饱和度与意义饱和度:多少次访谈才算足够?
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What is personalized medicine: sharpening a vague term based on a systematic literature review.什么是个性化医学:基于系统文献回顾来明晰一个模糊的术语。
BMC Med Ethics. 2013 Dec 21;14:55. doi: 10.1186/1472-6939-14-55.