离心式血液成分分离装置的比较功能

Comparative function of centrifugal apheresis devices.

作者信息

Rock G, Blanchette V, McCombie N, Tittley P

出版信息

Vox Sang. 1985;48(3):136-42. doi: 10.1111/j.1423-0410.1985.tb00160.x.

DOI:10.1111/j.1423-0410.1985.tb00160.x

Abstract

The function of four apheresis devices has been evaluated to obtain comparative data on performance and safety. Granulocyte yields were highest with the CS-3000 with 1.7 X 10(10) cells, but this preparation also contained 4.5 X 10(11) platelets; plateletpheresis gave ranges of 3.4 X 10(11) to 4.5 X 10(11) cells. The amount of blood processed to obtain these yields varied greatly, ranging from 2.4 to 7 liters. Studies done on the donor return line showed no significant effects of the process. Comparative results on the efficacy of plasma exchange showed relatively little red cell contamination with any of these devices, but significant (6.9 X 10(10) platelet removal in the Fenwal bag.

摘要

已对四种血液分离设备的功能进行了评估，以获取有关性能和安全性的比较数据。使用CS - 3000时粒细胞产量最高，为1.7×10¹⁰个细胞，但该制剂中还含有4.5×10¹¹个血小板；血小板单采的细胞数量范围为3.4×10¹¹至4.5×10¹¹个。为获得这些产量所处理的血液量差异很大，从2.4升至7升不等。对供体回输管路进行的研究表明该过程没有显著影响。血浆置换疗效的比较结果显示，使用这些设备中的任何一种，红细胞污染相对较少，但在Fenwal袋中有显著的（6.9×10¹⁰）血小板清除。