Siostrzonek P, Klieber M, Niessner H
Wien Klin Wochenschr. 1985 Jan 18;97(2):76-83.
ADP and collagen induced platelet aggregation (PA) was studied in 18 patients suffering from arterial occlusive disease (stage II Fontaine) before and after a standardized treadmill test before and after 24 days of exercise training. At the beginning of this therapy collagen induced PA after treadmill testing was increased (amplitude +11.29%, p less than 0.05, maximal slope +18.57%, p less than 0.05, integrated area +15.23%, p less than 0.05), whereas ADP induced PA showed no consistent alteration. After the 24-day treatment period increase in collagen induced PA was considerably smaller (amplitude +7.48%, n.s., maximal slope +7.35%, n.s., integrated area +11.99%, p less than 0.05), whereas ADP induced PA again showed no consistent changes. Since the treadmill exercise induced PA showed a negative linear correlation with the claudication provoking walking distance the smaller increase in PA after treatment was considered to be due to the improved metabolic situation following exercise therapy.
在18例患有动脉闭塞性疾病（Fontaine II期）的患者中，研究了标准化跑步机测试前后以及运动训练24天后，二磷酸腺苷（ADP）和胶原诱导的血小板聚集（PA）情况。在该治疗开始时，跑步机测试后胶原诱导的PA增加（幅度增加11.29%，p<0.05；最大斜率增加18.57%，p<0.05；积分面积增加15.23%，p<0.05），而ADP诱导的PA无一致变化。经过24天的治疗期后，胶原诱导的PA增加幅度明显变小（幅度增加7.48%，无统计学意义；最大斜率增加7.35%，无统计学意义；积分面积增加11.99%，p<0.05），而ADP诱导的PA再次无一致变化。由于跑步机运动诱导的PA与引发跛行的步行距离呈负线性相关，因此治疗后PA增加幅度较小被认为是运动疗法后代谢状况改善所致。
