Powell Neil, Blank Michael, Luintel Akish, Elkhalifa Shuayb, Bhogal Rashmeet, Wilcock Michael, Wakefield Michael, Sandoe Jonathan
Pharmacy Department, Royal Cornwall Hospital Trust, Truro, Cornwall, UK.
Imperial College Healthcare NHS Trust, London, UK.
NPJ Antimicrob Resist. 2024 Jul 10;2(1):18. doi: 10.1038/s44259-024-00035-6.
This article outlines recent developments in non-allergist delivered penicillin allergy de-labelling (PADL), discusses remaining controversies and uncertainties and explores the future for non-allergist delivered PADL. Recent developments include national guidelines for non-allergist delivered PADL and validation of penicillin allergy risk assessment tools. Controversies remain on which penicillin allergy features are low risk of genuine allergy. In the future genetic or immunological tests may facilitate PADL.
本文概述了非过敏专科医生进行青霉素过敏重新评估（PADL）的最新进展，讨论了尚存的争议和不确定性，并探讨了非过敏专科医生进行PADL的未来发展。最新进展包括非过敏专科医生进行PADL的国家指南以及青霉素过敏风险评估工具的验证。关于哪些青霉素过敏特征真正过敏风险较低仍存在争议。未来，基因或免疫检测可能会促进PADL的发展。
