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病例报告:左心房转移性鳞状细胞癌。

Case Report: Metastatic squamous cell carcinoma in the left atrium.

作者信息

Luo Shuai, Tian Xiaoxue, Xu Ting, Wang Jinjing

机构信息

Department of Pathology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.

出版信息

Front Cardiovasc Med. 2025 Jan 8;11:1500108. doi: 10.3389/fcvm.2024.1500108. eCollection 2024.

DOI:10.3389/fcvm.2024.1500108
PMID:39844903
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11750786/
Abstract

BACKGROUND

Metastatic tumours are the most common malignant tumours affecting the heart. Cardiac metastatic tumour progression is rapid, with no specific treatments available, and the prognosis is typically poor. Significant challenges remain in the diagnosis and treatment of cardiac metastases.

CASE DEMONSTRATION

A 52-year-old female presented with a history of exertion palpitations lasting over 2 months, worsened by cough and expectoration for 3 days. Colour Doppler echocardiography revealed a hypoechoic mass in the left atrium, which was excised. Postoperative pathology confirmed metastatic squamous cell carcinoma of the left atrium. Six months after surgical removal, the patient remained in good general condition.

CONCLUSION

Intracardiac metastasis is extremely rare and presents with non-specific clinical symptoms, often leading to oversight by clinicians. Early diagnosis relies on imaging studies, while definitive diagnosis requires pathological examination. Timely detection is crucial to improving patient prognosis.

摘要

背景

转移性肿瘤是影响心脏的最常见恶性肿瘤。心脏转移性肿瘤进展迅速,没有可用的特异性治疗方法,预后通常较差。心脏转移瘤的诊断和治疗仍然面临重大挑战。

病例展示

一名52岁女性,有劳力性心悸病史超过2个月,咳嗽咳痰3天加重。彩色多普勒超声心动图显示左心房有一低回声团块,予以切除。术后病理证实为左心房转移性鳞状细胞癌。手术切除6个月后,患者一般状况良好。

结论

心脏内转移极为罕见,临床表现无特异性,常导致临床医生漏诊。早期诊断依赖影像学检查,而明确诊断需要病理检查。及时发现对改善患者预后至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f45d/11750786/cbea44485d43/fcvm-11-1500108-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f45d/11750786/12ceda21b406/fcvm-11-1500108-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f45d/11750786/f9fad2f66c34/fcvm-11-1500108-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f45d/11750786/6a20c50b0dd7/fcvm-11-1500108-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f45d/11750786/5561495fc5c2/fcvm-11-1500108-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f45d/11750786/a19ab545e25c/fcvm-11-1500108-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f45d/11750786/cbea44485d43/fcvm-11-1500108-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f45d/11750786/12ceda21b406/fcvm-11-1500108-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f45d/11750786/f9fad2f66c34/fcvm-11-1500108-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f45d/11750786/6a20c50b0dd7/fcvm-11-1500108-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f45d/11750786/5561495fc5c2/fcvm-11-1500108-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f45d/11750786/a19ab545e25c/fcvm-11-1500108-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f45d/11750786/cbea44485d43/fcvm-11-1500108-g006.jpg

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本文引用的文献

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Esophageal Cancer With Cardiac Metastasis: Approach to Cardiac Masses in Patients With a Known Malignancy.伴有心脏转移的食管癌:已知恶性肿瘤患者心脏肿物的处理方法
Cureus. 2024 Jul 13;16(7):e64486. doi: 10.7759/cureus.64486. eCollection 2024 Jul.
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Case Report: Primary malignant mesothelioma of the left atrium easily misdiagnosed as myxoma.病例报告:左心房原发性恶性间皮瘤易误诊为黏液瘤。
Front Cardiovasc Med. 2024 Jun 13;11:1398311. doi: 10.3389/fcvm.2024.1398311. eCollection 2024.
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Right and left atrial metastasis of renal cell carcinoma: A case report.
肾细胞癌的左右心房转移:一例报告。
Int J Surg Case Rep. 2022 Oct;99:107692. doi: 10.1016/j.ijscr.2022.107692. Epub 2022 Sep 20.
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Mysterious Left Atrial Mass in a Patient With Metastatic Prostate Cancer.一名转移性前列腺癌患者的神秘左心房肿物
Cureus. 2022 Mar 16;14(3):e23238. doi: 10.7759/cureus.23238. eCollection 2022 Mar.
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[Metastatic Cardiac Tumor in the Left Atrium from Esophageal Cancer].[食管癌转移至左心房的心脏肿瘤]
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Systematic Review: Cardiac Metastasis of Lingual Squamous Cell Carcinoma.系统评价:舌鳞状细胞癌的心脏转移
Spartan Med Res J. 2021 Aug 30;6(2):27297. doi: 10.51894/001c.27297. eCollection 2021.
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Metastasectomy of left atrial mesenchymal chondrosarcoma.左房间叶性软骨肉瘤的转移瘤切除术
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