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激光针灸治疗骨关节炎的疗效与安全性:一项系统评价与Meta分析

Efficacy and safety of laser acupuncture on osteoarthritis: a systematic review and meta-analysis.

作者信息

Wen Xiangdong, Zhang Guojiang, Cui Jinquan, Tang Yuzhe, Meng Qi, Su Yang, An Senbo, Sun Shui

机构信息

Department of Joint Surgery, Shandong Provincial Hospital, Shandong University, Jinan, Shandong, China.

Department of Joint Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.

出版信息

Front Aging Neurosci. 2025 Jan 8;16:1462411. doi: 10.3389/fnagi.2024.1462411. eCollection 2024.

DOI:10.3389/fnagi.2024.1462411
PMID:39845448
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11751068/
Abstract

OBJECTIVES

To perform a meta-analysis of previous studies investigating the effects of laser acupuncture on osteoarthritis.

STUDY DESIGN

Systematic review and meta-analysis.

METHODS

Randomized controlled trials (RCTS) on laser acupuncture for osteoarthritis were searched in the databases of PubMed, Embase, Cochrane Library, and Web of Science with a search deadline of 24 December 2023. After identifying 11 studies, we used Stata 15.0 to analyze the data.

RESULTS

In the 11 studies identified, 931 patients were analyzed. Results showed that laser acupuncture significantly improved patients' pain and function compared to the placebo laser group. There were significant differences in VAS pain scores[SMD = -0.924, 95% CI (-1.200, -0.649),  = 0.000], WOMAC pain scores[SMD = -0.425, 95% CI (-0.652, -0.199),  = 0.000], WOMAC function scores[SMD = -0.307, 95% CI (-0.548, -0.065),  = 0.013], WOMAC stiffness scores[SMD = -0.235, 95% CI (-0.388, -0.083),  = 0.002] between the laser acupuncture group and the placebo laser group. The therapeutic effect of laser acupuncture disappeared at 8 weeks. In subgroup analysis, patients who received laser acupuncture with specific parameters had better VAS scores and WOMAC scores than patients in other subgroups.

CONCLUSION

The application of laser acupuncture can improve knee pain and function in patients with osteoarthritis in the short term. It is recommended to use a laser with a power greater than 100 mW and a wavelength greater than 1,000 nm. CO2 lasers and solid-state lasers were shown to be more effective in the results than other types of lasers.

摘要

目的

对既往研究激光针刺治疗骨关节炎效果的研究进行荟萃分析。

研究设计

系统评价与荟萃分析。

方法

在PubMed、Embase、Cochrane图书馆和Web of Science数据库中检索截至2023年12月24日关于激光针刺治疗骨关节炎的随机对照试验(RCT)。在确定11项研究后,我们使用Stata 15.0进行数据分析。

结果

在纳入的11项研究中,共分析了931例患者。结果显示,与安慰剂激光组相比,激光针刺显著改善了患者的疼痛和功能。激光针刺组与安慰剂激光组在视觉模拟评分法(VAS)疼痛评分[标准化均数差(SMD)=-0.924,95%置信区间(CI)(-1.200,-0.649),P=0.000]、西安大略和麦克马斯特大学骨关节炎指数(WOMAC)疼痛评分[SMD=-0.425,95%CI(-0.652,-0.199),P=0.000]、WOMAC功能评分[SMD=-0.307,95%CI(-0.548,-0.065),P=0.013]、WOMAC僵硬评分[SMD=-0.235,95%CI(-0.388,-0.083),P=0.002]方面存在显著差异。激光针刺的治疗效果在8周时消失。在亚组分析中,接受特定参数激光针刺的患者的VAS评分和WOMAC评分优于其他亚组的患者。

结论

激光针刺的应用可在短期内改善骨关节炎患者的膝关节疼痛和功能。建议使用功率大于100 mW、波长大于1000 nm的激光。结果显示,二氧化碳激光和固态激光比其他类型的激光更有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3b9/11751068/526d8534486b/fnagi-16-1462411-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3b9/11751068/005cc0b681e3/fnagi-16-1462411-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3b9/11751068/15f8bb069b6c/fnagi-16-1462411-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3b9/11751068/1ddc8f486c1b/fnagi-16-1462411-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3b9/11751068/62d38d3a9fea/fnagi-16-1462411-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3b9/11751068/608bd178c9af/fnagi-16-1462411-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3b9/11751068/526d8534486b/fnagi-16-1462411-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3b9/11751068/005cc0b681e3/fnagi-16-1462411-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3b9/11751068/15f8bb069b6c/fnagi-16-1462411-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3b9/11751068/1ddc8f486c1b/fnagi-16-1462411-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3b9/11751068/62d38d3a9fea/fnagi-16-1462411-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3b9/11751068/608bd178c9af/fnagi-16-1462411-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3b9/11751068/526d8534486b/fnagi-16-1462411-g007.jpg

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