Dastenaie Fatemeh Davoudi, Javaheri Fatemeh Sadat Hashemi, Masoumvand Mohammad, Manesh Mohammad Amin Nazari, Moghadam Mohammad Akbari, Khosravi Maryam, Esfehani Ali Jafarzadeh
Department of Clinical Nutrition, School of Medicine Mashhad University of Medical Sciences Mashhad Khorasan Razavi Iran.
Student Research Committee Mshhad University of Medical Sciences Mashhad Iran.
Health Sci Rep. 2025 Jan 22;8(1):e70373. doi: 10.1002/hsr2.70373. eCollection 2025 Jan.
The protective effect of a healthy diet against chronic diseases has been confirmed in several primary studies. This study identifies the dominant food patterns using factor analysis and determining its relationship with metabolic syndrome in female employees participating in the Persian cohort study.
Female participants with metabolic syndrome (based on the National Cholesterol Education Program (NCEP ATP III) were studied using a cross-sectional design. Demographic, clinical and anthropometric information of the subjects were analyzed after checking the inclusion and exclusion criteria. Also, dietary intake based on the food frequency questionnaire (FFQ) was extracted from the participants' records.
Waist circumference and HDL were significantly correlated with the healthy food pattern ( < 0.05). In the unadjusted model, a significant relationship was observed between healthy food patterns and low HDL ( = 0.035, OR = 0.674, 95% CI for OR: 0.467-0.973). After adjusting for confounding factors, a significant relationship was observed between low HDL and the third and fourth quartiles of healthy food pattern ( < 0.001, OR = 420, 95% CI for OR: 0.257-0.684, and < 0.001, OR = 0.294, 95% CI for OR: 0.148-0.585, respectively), indicating that being in the third and fourth quartiles of dietary health was associated with 58% and 70.6% decreased risk of low HDL, respectively.
The results indicated that only healthy dietary patterns could have a preventive role against low HDL criterion of the metabolic syndrome among women.
多项初步研究已证实健康饮食对慢性病具有保护作用。本研究通过因子分析确定主要食物模式,并确定其与参与波斯队列研究的女性员工代谢综合征之间的关系。
采用横断面设计对患有代谢综合征(基于美国国家胆固醇教育计划(NCEP ATP III))的女性参与者进行研究。在检查纳入和排除标准后,分析了受试者的人口统计学、临床和人体测量信息。此外,还从参与者的记录中提取了基于食物频率问卷(FFQ)的饮食摄入量。
腰围和高密度脂蛋白与健康食物模式显著相关(<0.05)。在未调整模型中,观察到健康食物模式与低高密度脂蛋白之间存在显著关系(=0.035,比值比=0.674,比值比的95%置信区间:0.467-0.973)。在调整混杂因素后,观察到低高密度脂蛋白与健康食物模式的第三和第四四分位数之间存在显著关系(<0.001,比值比=420,比值比的95%置信区间:0.257-0.684,以及<0.001,比值比=0.294,比值比的95%置信区间:0.148-0.585),这表明饮食健康处于第三和第四四分位数分别与低高密度脂蛋白风险降低58%和70.6%相关。
结果表明,只有健康的饮食模式对女性代谢综合征的低高密度脂蛋白标准具有预防作用。