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[芬那西泮对酒精戒断综合征患者夜间睡眠的影响]

[Effect of phenazepam on the nocturnal sleep of patients with the alcoholic abstinence syndrome].

作者信息

Danilin V P, Krylov E N, Magalif A Iu, Raĭt M L

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1985;85(2):263-6.

PMID:3984615
Abstract

The authors studied the effect of phenazepam, a benzodiazepine derivative, on sleep disorders in alcoholic patients at the first period following alcohol intake discontinuation. Polygraphic registration of the sleep pattern was performed for two nights in 18 patients, receiving the drug and in ten patients of the control group. The drug use was associated with the following events: the latent period of falling asleep diminished, the total duration of sleep increased, the duration of consciousness "inside the sleep" decreased. As a result of the second stage recovery, the duration of the phase of slow sleep enhanced with no evidence of delta-sleep recovery. The duration of the fast sleep phase increased. The patients showed a marked improvement of sleep quality.

摘要

作者研究了苯二氮䓬衍生物非那西泮对戒酒初期酒精性患者睡眠障碍的影响。对18名服用该药物的患者和10名对照组患者进行了两晚的睡眠模式多导记录。使用该药物与以下情况相关:入睡潜伏期缩短,总睡眠时间增加,“睡眠中”意识持续时间减少。由于第二阶段的恢复,慢睡眠阶段的持续时间增加,且无δ睡眠恢复的证据。快睡眠阶段的持续时间增加。患者的睡眠质量有明显改善。

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