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用于胃肠疾病诊断与治疗的纳米超声检查术的最新进展。

Recent advances in nanoultrasonography for the diagnosis and treatment of gastrointestinal diseases.

作者信息

Wan Weiping, Tao Haina, Chen Zhixiao, Guo Fangming, Tian Yun

机构信息

Department of Ultrasound, Yantaishan Hospital, Binzhou Medical University, Yantai, Shandong, China.

Department of Gastroenterology, Yantaishan Hospital, Binzhou Medical University, Yantai, Shandong, China.

出版信息

Nanomedicine (Lond). 2025 Mar;20(5):519-530. doi: 10.1080/17435889.2025.2457319. Epub 2025 Jan 23.

DOI:10.1080/17435889.2025.2457319
PMID:39846205
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11875487/
Abstract

With the rapid development of nanotechnology, nanoultrasonography has emerged as a promising medical imaging technique that demonstrates significant potential in the diagnosis and treatment of gastrointestinal (GI) diseases. This review discusses the applications of nanoultrasonography in the gastrointestinal field, including improvements in imaging resolution, diagnostic accuracy, latest research findings, and prospects for clinical application. By analyzing existing literature, we explore the role of nanoultrasonography in enhancing imaging resolution, enabling targeted drug delivery, and improving therapeutic outcomes, thereby providing a reference for future research directions.

摘要

随着纳米技术的迅速发展,纳米超声成像已成为一种很有前景的医学成像技术,在胃肠道疾病的诊断和治疗中显示出巨大潜力。本文综述讨论了纳米超声成像在胃肠道领域的应用,包括成像分辨率的提高、诊断准确性、最新研究成果以及临床应用前景。通过分析现有文献,我们探讨了纳米超声成像在提高成像分辨率、实现靶向给药和改善治疗效果方面的作用,从而为未来的研究方向提供参考。

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本文引用的文献

1
Application of nanoultrasonography in early diagnosis of coronary heart disease.纳米超声心动图在冠心病早期诊断中的应用。
Nanomedicine (Lond). 2025 Jan;20(1):79-89. doi: 10.1080/17435889.2024.2435255. Epub 2024 Dec 5.
2
Temperature and Ultrasound-Responsive Nanoassemblies for Enhanced Organ Targeting and Reduced Cardiac Toxicity.温度和超声响应型纳米组装体用于增强器官靶向和降低心脏毒性。
Int J Nanomedicine. 2024 Nov 6;19:11397-11413. doi: 10.2147/IJN.S470465. eCollection 2024.
3
Novel anti-CEA affibody for rapid tumor-targeting and molecular imaging diagnosis in mice bearing gastrointestinal cancer cell lines.用于携带胃肠道癌细胞系小鼠的快速肿瘤靶向和分子成像诊断的新型抗癌胚抗原亲和体
Front Microbiol. 2024 Oct 9;15:1464088. doi: 10.3389/fmicb.2024.1464088. eCollection 2024.
4
Ultrasound-Driven Nanomachine for Enhanced Sonodynamic Therapy of Non-Small-Cell Lung Cancer.超声驱动纳米机器增强非小细胞肺癌的声动力学治疗。
ACS Appl Mater Interfaces. 2024 Nov 6;16(44):59803-59813. doi: 10.1021/acsami.4c11546. Epub 2024 Oct 22.
5
Application of F-fluorodeoxyglucose positron emission tomography/computed tomography imaging in recurrent anastomotic tumors after surgery in digestive tract tumors.F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描成像在消化道肿瘤术后吻合口复发肿瘤中的应用
World J Gastrointest Surg. 2024 Aug 27;16(8):2474-2483. doi: 10.4240/wjgs.v16.i8.2474.
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Laser fragmentation of amorphous and crystalline selenium of various morphologies and assessment of their antioxidant and protection properties.不同形态的非晶态和晶态硒的激光破碎及其抗氧化和保护性能评估。
Front Chem. 2024 Aug 9;12:1459477. doi: 10.3389/fchem.2024.1459477. eCollection 2024.
7
Photoluminescence Quenching Upon Growth of Metal Nanoparticles: Quantum-Mechanical Views.金属纳米颗粒生长过程中的光致发光猝灭:量子力学观点。
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Bioact Mater. 2024 May 25;39:317-335. doi: 10.1016/j.bioactmat.2024.05.035. eCollection 2024 Sep.
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Conventional versus Hepatic Arteriography and C-Arm CT-Guided Ablation of Liver Tumors (HepACAGA): A Comparative Analysis.传统方法与肝动脉造影及C形臂CT引导下肝肿瘤消融术(HepACAGA)的比较分析
Cancers (Basel). 2024 May 18;16(10):1925. doi: 10.3390/cancers16101925.
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Long-Term Accumulation, Biological Effects and Toxicity of BSA-Coated Gold Nanoparticles in the Mouse Liver, Spleen, and Kidneys.BSA 包覆金纳米粒子在小鼠肝、脾和肾脏中的长期积累、生物效应和毒性。
Int J Nanomedicine. 2024 May 8;19:4103-4120. doi: 10.2147/IJN.S443168. eCollection 2024.