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共生生物可吸收装置的进展

Advances in Symbiotic Bioabsorbable Devices.

作者信息

Zhu Chang, Wang Engui, Li Zhou, Ouyang Han

机构信息

School of Nanoscience and Engineering, School of Chemical Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China.

Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing, 101400, China.

出版信息

Adv Sci (Weinh). 2025 Jun;12(24):e2410289. doi: 10.1002/advs.202410289. Epub 2025 Jan 23.

DOI:10.1002/advs.202410289
PMID:39846424
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12199594/
Abstract

Symbiotic bioabsorbable devices are ideal for temporary treatment. This eliminates the boundaries between the device and organism and develops a symbiotic relationship by degrading nutrients that directly enter the cells, tissues, and body to avoid the hazards of device retention. Symbiotic bioresorbable electronics show great promise for sensing, diagnostics, therapy, and rehabilitation, as underpinned by innovations in materials, devices, and systems. This review focuses on recent advances in bioabsorbable devices. Innovation is focused on the material, device, and system levels. Significant advances in biomedical applications are reviewed, including integrated diagnostics, tissue repair, cardiac pacing, and neurostimulation. In addition to the material, device, and system issues, the challenges and trends in symbiotic bioresorbable electronics are discussed.

摘要

共生生物可吸收装置非常适合临时治疗。这消除了装置与生物体之间的界限，并通过降解直接进入细胞、组织和身体的营养物质建立共生关系，以避免装置留存的危害。共生生物可吸收电子器件在传感、诊断、治疗和康复方面显示出巨大潜力，这得益于材料、器件和系统方面的创新。本综述聚焦于生物可吸收装置的最新进展。创新集中在材料、器件和系统层面。综述了生物医学应用方面的重大进展，包括集成诊断、组织修复、心脏起搏和神经刺激。除了材料、器件和系统问题外，还讨论了共生生物可吸收电子器件面临的挑战和发展趋势。

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