Hwang Yu-Jeong, Moon Bo-Youn, Kim Ji-In, Ali Md Sekendar, Song Hyun-Ju, Lee Yeon-Hee, Choi Ji-Hyun, Kang Hee-Seung, Park Hyeon-Jung, Kim Jae-Myung, Lim Suk-Kyung
Department of Animal and Plant Quarantine Agency, Bacterial Disease Division, Gimcheon-si, Republic of Korea.
Foodborne Pathog Dis. 2025 Jan 23. doi: 10.1089/fpd.2024.0168.
Antimicrobial-resistant bacterial contamination of meat poses a significant global public health risk. We aimed to determine antimicrobial resistance profiles and trends of recovered from carcasses of healthy food-producing animals in South Korea during 2010-2023. In total, 4748 isolates obtained from cattle ( = 1582), pigs ( = 1572), and chickens ( = 1594) were assessed for susceptibility to 12 antimicrobials. Antimicrobial resistance was different among samples. Overall, antimicrobial resistance was high in pigs and chicken carcasses. More than about 80% of isolates from pigs and chickens exhibited resistance to one or more antimicrobials. Among the tested antimicrobials, resistance to ampicillin, chloramphenicol, streptomycin, and tetracycline was significantly higher in pigs and chickens compared with cattle ( < 0.05). Moreover, chicken isolates showed much higher resistance to nalidixic acid and ciprofloxacin than other samples. Resistance to critically important antimicrobials, colistin, remained less than about 1%, while resistance to ceftiofur showed increased trends in pig and chicken samples. Higher multidrug-resistant (MDR) isolates were identified in chickens and pigs compared with cattle ( < 0.05). Furthermore, most MDR patterns include streptomycin and tetracycline resistance. MDR contaminating meat during slaughter can be transmitted to humans via the food chain. Thus, prudent use of antimicrobials and proper hygienic practices are urgently needed to reduce the risk of transmission.
肉类中的抗菌药物耐药性细菌污染对全球公共卫生构成重大风险。我们旨在确定2010 - 2023年期间从韩国健康食用动物胴体中分离出的细菌的抗菌药物耐药性概况和趋势。总共对从牛（n = 1582）、猪（n = 1572）和鸡（n = 1594）中获得的4748株分离菌进行了12种抗菌药物的敏感性评估。不同样本之间的抗菌药物耐药性存在差异。总体而言，猪和鸡胴体中的抗菌药物耐药性较高。来自猪和鸡的分离菌中超过约80%对一种或多种抗菌药物表现出耐药性。在测试的抗菌药物中，猪和鸡对氨苄西林、氯霉素、链霉素和四环素的耐药性显著高于牛（P < 0.05）。此外，鸡的分离菌对萘啶酸和环丙沙星表现出比其他样本更高的耐药性。对极为重要的抗菌药物黏菌素的耐药性仍低于约1%，而猪和鸡样本中对头孢噻呋的耐药性呈上升趋势。与牛相比，在鸡和猪中鉴定出更高比例的多重耐药（MDR）分离菌（P < 0.05）。此外，大多数MDR模式包括对链霉素和四环素的耐药性。屠宰过程中污染肉类的MDR细菌可通过食物链传播给人类。因此，迫切需要谨慎使用抗菌药物并采取适当的卫生措施以降低传播风险。
