Li Zi-Ling, Qi Xiao-Run, Xu Yi-Heng, Zhao Jia-Qi, Zuo Gui-Fu, Wang Man-Man
School of Public Health, Hebei Key Laboratory of Occupational Health and Safety for Coal Industry, North China University of Science and Technology, Tangshan 063210, Hebei, China.
College of Materials Science and Engineering, North China University of Science and Technology, Tangshan 063210, Hebei, China.
Food Chem. 2025 Apr 30;472:142904. doi: 10.1016/j.foodchem.2025.142904. Epub 2025 Jan 18.
Effective and convenient QuEChERS of lipophilic pesticides with wide pK range from strongly pigment-rich food samples remains a great challenge. Here, a ZIF-67 derived magnetic nanoporous carbon (Co@MPC) was firstly proposed for modified QuEChERS of carbamate pesticides (pK 4.3-12.3) in various vegetable and fruit samples prior to LC-MS/MS. This sorbent offered superior adsorption capacities of 29.89 mg/g and 22.28 mg/g towards chlorophyll and lutein via π-π and hydrophobic interactions. The present method exhibited acceptable matrix effect of -4.8 %-14.4 %, low detection limits of 0.003-0.02 μg/kg and satisfactory recoveries of 80.2 %-108 % in celery, cabbage, Chinese cabbage, apple, banana and orange samples. 10 mg of Co@MPC enabled highly efficient matrix purification and isolation in 20 s, offering low-cost and facile clean-up process. The study highlighted great potential of Co@MPC as QuEChERS sorbent, and demonstrated its wide applicability and broad application prospects to monitor the contaminants in food items.
从富含色素的食品样本中有效且便捷地萃取亲脂性农药（pK范围广泛，从强亲脂性到弱亲脂性）仍然是一项巨大挑战。在此，首次提出了一种由ZIF-67衍生的磁性纳米多孔碳（Co@MPC），用于在LC-MS/MS分析之前对各种蔬菜和水果样本中的氨基甲酸酯类农药（pK 4.3-12.3）进行改良的QuEChERS萃取。这种吸附剂通过π-π和疏水相互作用对叶绿素和叶黄素具有29.89 mg/g和22.28 mg/g的优异吸附容量。本方法在芹菜、卷心菜、大白菜、苹果、香蕉和橙子样本中表现出-4.8%-14.4%的可接受基质效应、0.003-0.02 μg/kg的低检测限以及80.2%-108%的满意回收率。10 mg的Co@MPC能够在20秒内实现高效的基质净化和分离，提供低成本且简便的净化过程。该研究突出了Co@MPC作为QuEChERS吸附剂的巨大潜力，并证明了其在监测食品中污染物方面的广泛适用性和广阔应用前景。
