Limaiem Faten, Nefiss Mouadh, Bouzidi Ramzi
University of Tunis El Manar, Faculty of Medicine of Tunis, 1007, Tunisia; Pathology Department, Hospital Mongi Slim La Marsa, Tunisia.
University of Tunis El Manar, Faculty of Medicine of Tunis, 1007, Tunisia; Department of Orthopedic Surgery, Hospital Mongi Slim La Marsa, Tunisia.
Int J Surg Case Rep. 2025 Feb;127:110924. doi: 10.1016/j.ijscr.2025.110924. Epub 2025 Jan 22.
Osteoblastoma is a rare benign bone tumor, accounting for 1 % of primary bone tumors, often affecting the spine and sacrum. Accurate diagnosis is essential for appropriate treatment and prognosis.
A 19-year-old male presented with two years of persistent nocturnal radicular and low back pain unresponsive to anti-inflammatory medications. Physical examination revealed a left-sided gibbosity and a positive Sonnette sign at lumbar levels L3-L4 and L4-L5 without neurological deficits. MRI and CT scans revealed anomalies in the right facet joint at L3-L4 and a lytic lesion at the L3 inferior articular process, suggestive of osteoblastoma. The patient underwent en bloc resection of the right L3 inferior articular process, decompression of the right L3 root, and tumor curettage. A unilateral fixation with pedicle screws was performed to prevent instability. Histological examination confirmed osteoblastoma. The patient's postoperative recovery progressed moderately, and he is actively participating in physical therapy, with continued follow-up planned to monitor for any potential recurrence or complications.
Osteoblastoma diagnosis is based on clinical, radiological, and histopathological evaluation. It is important to distinguish osteoblastoma from similar tumors for appropriate management. Surgical intervention, including en bloc resection or curettage, is the treatment of choice based on clinical factors and tumor location.
This case highlights the challenges in diagnosing spinal osteoblastoma, especially in young patients with persistent back pain. Early recognition, prompt intervention, and surveillance are critical for optimal outcomes.
骨母细胞瘤是一种罕见的良性骨肿瘤,占原发性骨肿瘤的1%,常累及脊柱和骶骨。准确诊断对于恰当的治疗和预后至关重要。
一名19岁男性,持续两年夜间神经根性及下背部疼痛,抗炎药物治疗无效。体格检查发现左侧脊柱后凸,L3-L4和L4-L5腰椎水平Sonnette征阳性,无神经功能缺损。MRI和CT扫描显示L3-L4右侧小关节异常,L3下关节突有溶骨性病变,提示骨母细胞瘤。患者接受了L3右侧下关节突整块切除、L3右侧神经根减压及肿瘤刮除术。采用椎弓根螺钉进行单侧固定以防止不稳定。组织学检查确诊为骨母细胞瘤。患者术后恢复情况中等,目前正在积极参与物理治疗,并计划持续随访以监测任何潜在的复发或并发症。
骨母细胞瘤的诊断基于临床、影像学和组织病理学评估。为了进行恰当的管理,将骨母细胞瘤与相似肿瘤区分开来很重要。根据临床因素和肿瘤位置,手术干预,包括整块切除或刮除术,是首选的治疗方法。
本病例突出了诊断脊柱骨母细胞瘤的挑战,尤其是在患有持续性背痛的年轻患者中。早期识别、及时干预和监测对于获得最佳结果至关重要。