Abdelrahman Hanan, Qadire Mohammad Al
Manning College of Nursing and Health Sciences, University of Massachusetts Boston, Boston, MA; Faculty of Nursing, Suez Canal University, Ismailia, Egypt.
Faculty of Nursing, Al Al-Bayt University, Mafraq, Jordan.
Pain Manag Nurs. 2025 Jun;26(3):290-297. doi: 10.1016/j.pmn.2024.12.018. Epub 2025 Jan 23.
This study aimed to investigate pain characteristics, opioid misuse prevalence, and the relationship between healthliteracy and pain catastrophising in patients with Sickle Cell Disease (SCD).
This was a cross-sectional study.
Data were collected from patients with SCD in Oman. Validated tools were used to assess pain (Brief Pain Inventory), healthliteracy (HLS-Q12), opioid misuse (Current Opioid Misuse Measure [COMM]), and pain catastrophising (Pain Catastrophising Scale).
The study included 169 patients with SCD, with an average age of 34.4 (SD = 12.9) years, of whom 51.5% werefemale. A total of 79.3% of the participants reported experiencing pain, with an average total pain score of 3.8 (SD = 2.6).Additionally, 74% of the patients were identified as being at risk of opioid misuse. The risk of opioid misuse was positivelyassociated with pain catastrophising (r = 0.302, p < 0.001) and negatively associated with health literacy (r = -0.220, p = 0.005). Pain severity and interference are also linked to the risk of opioid misuse. Sociodemographic factors, such as age, sex, and education, showed no significant association with the risk of opioid misuse.
Patients with SCD face high rates of chronic pain and considerable risk of opioid misuse. Psychological factors, particularly pain catastrophising and lower healthliteracy, were strongly associated with misuse risk, while sociodemographic factors had less impact.
These findings highlight the need for targeted interventions addressing psychological support and health literacy to reduce opioidmisuse in SCD patients. Healthcare providers should integrate pain management strategies with educational programs to enhancehealth literacy and mitigate the psychological burden of pain.
本研究旨在调查镰状细胞病（SCD）患者的疼痛特征、阿片类药物滥用患病率，以及健康素养与疼痛灾难化之间的关系。
这是一项横断面研究。
从阿曼的SCD患者中收集数据。使用经过验证的工具来评估疼痛（简明疼痛量表）、健康素养（健康素养问卷简版[HLS-Q12]）、阿片类药物滥用（当前阿片类药物滥用测量量表[COMM]）和疼痛灾难化（疼痛灾难化量表）。
该研究纳入了169例SCD患者，平均年龄为34.4（标准差 = 12.9）岁，其中51.5%为女性。共有79.3%的参与者报告经历过疼痛，平均总疼痛评分为3.8（标准差 = 2.6）。此外，74%的患者被确定有阿片类药物滥用风险。阿片类药物滥用风险与疼痛灾难化呈正相关（r = 0.302，p < 0.001），与健康素养呈负相关（r = -0.220，p = 0.005）。疼痛严重程度和干扰也与阿片类药物滥用风险相关。年龄、性别和教育程度等社会人口学因素与阿片类药物滥用风险无显著关联。
SCD患者面临着较高的慢性疼痛发生率和相当大的阿片类药物滥用风险。心理因素，尤其是疼痛灾难化和较低的健康素养，与滥用风险密切相关，而社会人口学因素的影响较小。
这些发现凸显了需要采取针对性干预措施，提供心理支持和提高健康素养，以减少SCD患者的阿片类药物滥用。医疗保健提供者应将疼痛管理策略与教育项目相结合，以提高健康素养并减轻疼痛的心理负担。
