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矿工中矽肺结核的危险因素:一项范围综述

Risk factors for silicotuberculosis among miners: a scoping review.

作者信息

Saliba Mansour F, Karam Zeina Z, Khayat Moussa El, Koka Elizabeth, Halwani Dana A, Ghanawi Joly, Hneiny Layal, Jurdi Mey, Dhaini Hassan R, Musharrafieh Umayya, Habib Rima R

机构信息

Department of Environmental Health, Faculty of Health Sciences, American University of Beirut, Beirut, 1107 2020, Lebanon.

American University of Beirut, Beirut, 1107 2020, Lebanon.

出版信息

BMC Public Health. 2025 Jan 23;25(1):287. doi: 10.1186/s12889-025-21362-x.

Abstract

BACKGROUND

Miners exposed to silica dust are susceptible to silicotuberculosis (STB) outcome - the development of tuberculosis (TB) in miners with silicosis. STB is an important occupational and public health issue in the twenty-first century. This scoping review aimed to map the risk factors associated with STB.

METHODS

A literature search was carried out to identify the available international literature on STB risk factors from four databases: MEDLINE, EMBASE, CINAHL, and COCHRANE LIBRARY. Various grey literature sources such as Google Scholar, Science.gov, and WHO Global Index Medicus were also searched. The main study outcome is STB; the selection criteria also included studies assessing TB and silicosis as comorbidities leading to STB.

RESULTS

The final review included 22 studies. Findings identified various STB risk factors including demographic factors such as age and sex, lifestyle factors including smoking and alcohol intake, clinical factors such as history of TB, grades of silicosis, and human immunodeficiency virus (HIV), in addition to occupational factors encompassing silica exposure, duration of employment, and type of work setting.

CONCLUSION

The findings of this scoping review highlight the research gaps in the reviewed literature, including the dearth of longitudinal studies focusing on the directionality of the two comorbidities (TB and silicosis) that lead to STB, lack of gender considerations in research on this topic, and an absence of articles on vulnerable populations including children. The findings of this review may help guide future research and inform occupational health and safety policies addressing STB outcomes among miners.

摘要

背景

接触二氧化硅粉尘的矿工易患硅肺结核(STB)——矽肺矿工中结核病(TB)的发生。STB是21世纪一个重要的职业和公共卫生问题。本综述旨在梳理与STB相关的风险因素。

方法

进行文献检索,以从四个数据库(MEDLINE、EMBASE、CINAHL和COCHRANE图书馆)中识别有关STB风险因素的现有国际文献。还检索了各种灰色文献来源,如谷歌学术、Science.gov和世界卫生组织全球医学索引。主要研究结果是STB;选择标准还包括评估结核病和矽肺作为导致STB的合并症的研究。

结果

最终综述纳入了22项研究。研究结果确定了各种STB风险因素,包括年龄和性别等人口统计学因素、吸烟和饮酒等生活方式因素、结核病病史、矽肺等级和人类免疫缺陷病毒(HIV)等临床因素,此外还包括二氧化硅暴露、就业时长和工作环境类型等职业因素。

结论

本综述的结果突出了所审查文献中的研究空白,包括缺乏关注导致STB的两种合并症(结核病和矽肺)方向性的纵向研究、该主题研究中缺乏性别考量,以及没有关于包括儿童在内的弱势群体的文章。本综述的结果可能有助于指导未来的研究,并为解决矿工中STB问题的职业健康与安全政策提供参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9517/11756151/2cfa1033916c/12889_2025_21362_Fig1_HTML.jpg

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