Hayne S T, Diestelmier M S, Johnson E A, Braund R R
Am J Clin Pathol. 1985 Apr;83(4):512-6. doi: 10.1093/ajcp/83.4.512.
Polycythemia vera and primary hyperparathyroidism is diagnosed in a patient with dysplastic nevus syndrome. A 59-year-old white man is noted to have numerous pigmented lesions found predominantly over the upper aspect of the back and chest. A biopsy revealed the atypical nevi found in dysplastic nevus syndrome. Over a 13-year period, three superficial spreading malignant melanomas were excised. The patient subsequently had polycythemia vera and primary hyperparathyroidism develop. Atypical pigmented skin lesions were not seen in family members, although two family members died of metastatic malignant neoplasms, one from endometrial carcinoma and the second from prostatic adenocarcinoma.
一名患有发育异常痣综合征的患者被诊断出患有真性红细胞增多症和原发性甲状旁腺功能亢进。一名59岁的白人男性被发现背部和胸部上半部分有大量色素沉着病变。活检显示为发育异常痣综合征中的非典型痣。在13年的时间里，切除了3例浅表扩散性恶性黑色素瘤。该患者随后患上了真性红细胞增多症和原发性甲状旁腺功能亢进。家庭成员中未见非典型色素沉着性皮肤病变，不过有两名家庭成员死于转移性恶性肿瘤，一名死于子宫内膜癌，另一名死于前列腺腺癌。
