Hutchens K S, Küng M
Am J Med. 1985 Apr;78(4):715-8. doi: 10.1016/0002-9343(85)90421-8.
A young patient presented with unconsciousness, cardiac arrhythmias, arterial hypotension, and mild intravascular hemolysis after intentional inhalation of chloroform. After the initial complications had resolved, nausea, loss of appetite, and mild transitory jaundice developed. Chloroform-associated hepatotoxicity was biochemically and histologically documented. Facilitating factors included long-term moderate alcohol consumption and an initial episode of arterial hypoxemia. Chloroform inhalation for recreational purposes is probably uncommon. Yet, because of its delayed onset, chloroform poisoning should be considered in acute liver disease without a clear antecedent cause.
一名年轻患者在故意吸入氯仿后出现昏迷、心律失常、动脉低血压和轻度血管内溶血。初始并发症缓解后，出现恶心、食欲不振和轻度短暂性黄疸。氯仿相关的肝毒性在生化和组织学上得到了证实。促成因素包括长期适度饮酒和最初的动脉低氧血症发作。出于娱乐目的吸入氯仿可能并不常见。然而，由于其发病延迟，对于无明确先行病因的急性肝病，应考虑氯仿中毒。
