氯仿摄入后的诊断性放射不透光性和肝毒性：一例报告
Diagnostic radiopacity and hepatotoxicity following chloroform ingestion: a case report.
作者信息
Choi S H, Lee S W, Hong Y S, Kim S J, Moon S W, Moon J D
机构信息
Department of Emergency Medicine, College of Medicine, Korea University, Seoul, Korea.
出版信息
Emerg Med J. 2006 May;23(5):394-5. doi: 10.1136/emj.2005.027466.
BACKGROUND
Diagnostic imaging can help in the management of toxicologic emergencies. The authors report on a patient who presented to the emergency department with coma and suppressed respirations after ingestion of an unknown substance.
METHODS
Ingestion of chloroform with radiopaque material in the bowel on abdominal radiograph was documented. The patient was treated with haemoperfusion, activated charcoal, and laxatives to decrease the toxicities.
RESULTS
Hepatotoxicity occurred on post-ingestion day 3 and elevation of liver enzymes reached peak levels on post-ingestion day 5. The patient received N-acetylsystein and supportive care during hospitalisation. The patient improved from hepatic dysfunction and was discharged without complication on post-ingestion day 11.
CONCLUSION
Radiographic studies in toxicology may confirm a diagnosis and assist in therapeutic intervention.
背景
诊断性影像学检查有助于中毒急症的处理。作者报告了一名患者，其在摄入未知物质后出现昏迷和呼吸抑制，被送往急诊科。
方法
腹部X线片显示肠道内有不透X线物质，提示摄入了氯仿。患者接受了血液灌流、活性炭和泻药治疗以减轻毒性。
结果
摄入后第3天出现肝毒性，摄入后第5天肝酶升高达到峰值。患者住院期间接受了N - 乙酰半胱氨酸治疗和支持性护理。患者肝功能障碍有所改善，摄入后第11天出院，无并发症。
结论
毒理学中的影像学研究可确诊并有助于治疗干预。
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