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源于脊柱旁的单中心Castleman病需与神经鞘瘤鉴别:病例报告

Unicentric Castleman's Disease of Paraspinal Origin Requiring Differentiation From Schwannoma: Case Report.

作者信息

Fujimoto Hazuki, Okamura Kayoko, Tauchi Shunsuke, Tsukamoto Rei, Kida Nanami, Ikeda Miho, Hatakeyama Yukihisa, Ohnishi Hisashi

机构信息

Department of Respiratory Medicine Akashi Medical Center Akashi Japan.

Department of Thoracic Surgery Akashi Medical Center Akashi Japan.

出版信息

Respirol Case Rep. 2025 Jan 23;13(1):e70099. doi: 10.1002/rcr2.70099. eCollection 2025 Jan.

Abstract

Unicentric Castleman's disease (UCD) typically presents as an asymptomatic tumour in the anterior or middle mediastinum. Occurrence in the paravertebral region is comparatively rare and it requires differentiation from neurogenic tumours by imaging. In our patient, preoperative imaging findings were atypical of schwannoma. Contrast-enhanced MRI of the thoracic region showed a muscle-like mass in contact with the pleura on T1-weighted images. T2-weighted images showed high signal, especially at the margins. Diffusion-weighted images showed diffusion restriction around the limbus, and contrast-enhanced T1-weighted images displayed strong enhancement of the mass. Diagnosis could not be made preoperatively, although UCD was suspected. Thoracoscopic tumour resection was performed for definitive diagnosis and treatment and postoperative diagnosis was hyaline-vascular-type UCD. Diagnosis of neurogenic tumours can be difficult by imaging alone. When imaging findings are atypical, a definitive diagnosis is required, with consideration of the possibility of UCD.

摘要

单中心Castleman病(UCD)通常表现为前纵隔或中纵隔的无症状肿瘤。发生在椎旁区域相对罕见,需要通过影像学与神经源性肿瘤鉴别。在我们的患者中,术前影像学表现不符合神经鞘瘤。胸部对比增强MRI在T1加权图像上显示一个与胸膜接触的肌肉样肿块。T2加权图像显示高信号,尤其是在边缘。扩散加权图像显示边缘周围有扩散受限,对比增强T1加权图像显示肿块有强烈强化。尽管怀疑是UCD,但术前无法确诊。为明确诊断和治疗进行了胸腔镜肿瘤切除术,术后诊断为透明血管型UCD。仅通过影像学诊断神经源性肿瘤可能困难。当影像学表现不典型时,需要明确诊断,并考虑UCD的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fc8/11756988/55963d783b46/RCR2-13-e70099-g002.jpg

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