Stein Elliot J, Mesenbring Elise, Smith Tracy, Hebbe Annika, Salahuddin Taufiq, Waldo Stephen W, Dyal Michael D, Doll Jacob A
Division of Cardiology, Department of Medicine, University of Washington Medical Center, Seattle (E.J.S., T. Salahuddin, J.A.D.).
VA Puget Sound Healthcare System, Seattle, WA (E.J.S., T. Salahuddin, J.A.D.).
Circ Cardiovasc Interv. 2025 Feb;18(2):e014528. doi: 10.1161/CIRCINTERVENTIONS.124.014528. Epub 2025 Jan 24.
Intravascular imaging (IVI) is widely recognized to improve outcomes after percutaneous coronary intervention (PCI). However, IVI is underutilized and is not yet established as a performance measure for quality PCI.
We examined temporal trends of IVI use for all PCIs performed at Veterans Affairs hospitals in the United States from 2010 to 2022 using retrospective observational cohorts. IVI was defined as intravascular ultrasound or optical coherence tomography. A contemporary subset of PCIs from 2020 to 2022 was used to examine clinical characteristics associated with IVI use and test the reliability of IVI as a pass/fail performance measure. We then used a generalized linear mixed model to estimate the proportion of IVI use variability attributable to the hospital, physician, and patient level. Cox proportional hazard models were used to assess the association of IVI with clinical outcomes at 1 year.
IVI use increased from 12.3% in 2010 to 43.1% in 2022 in 136 071 PCIs included in the study. Among 22 918 PCIs in the contemporary cohort, IVI was more frequent with nonemergent presentations, chronic total occlusions, and left main lesions but usage variability was primarily attributable to hospital (54%) and physician (33%) levels. As a pass/fail performance measure, reliability was high (>0.96) at hospital and physician levels. However, IVI use was not associated with statistically significant differences in mortality or major adverse cardiovascular events in this cohort.
IVI use for PCI is increasing rapidly at Veterans Affairs hospitals in the United States but with marked variation at the hospital and physician levels. IVI meets established criteria for an effective performance measure and should be measured and reported by local and national organizations to encourage further uptake. Ongoing training and quality improvement may be required to maximize the benefit of IVI as it is more widely utilized.
血管内成像(IVI)被广泛认为可改善经皮冠状动脉介入治疗(PCI)后的预后。然而,IVI的使用未得到充分利用,尚未被确立为高质量PCI的一项性能指标。
我们使用回顾性观察队列研究了2010年至2022年在美国退伍军人事务医院进行的所有PCI中IVI使用的时间趋势。IVI定义为血管内超声或光学相干断层扫描。使用2020年至2022年PCI的当代子集来检查与IVI使用相关的临床特征,并测试IVI作为通过/失败性能指标的可靠性。然后,我们使用广义线性混合模型来估计IVI使用变异性中可归因于医院、医生和患者层面的比例。使用Cox比例风险模型评估IVI与1年临床结局的关联。
在纳入研究的136071例PCI中,IVI的使用从2010年的12.3%增加到2022年的43.1%。在当代队列的22918例PCI中,非紧急情况、慢性完全闭塞和左主干病变时IVI使用更为频繁,但使用变异性主要归因于医院(54%)和医生(33%)层面。作为通过/失败性能指标,在医院和医生层面可靠性较高(>0.96)。然而,在该队列中,IVI的使用与死亡率或主要不良心血管事件的统计学显著差异无关。
在美国退伍军人事务医院,PCI中IVI的使用正在迅速增加,但在医院和医生层面存在显著差异。IVI符合有效性能指标的既定标准,地方和国家组织应进行测量和报告,以鼓励进一步采用。随着IVI得到更广泛应用,可能需要持续培训和质量改进以最大化其益处。