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脉络膜前动脉动脉瘤的管理:一项回顾性队列研究。

Management of Anterior Choroidal Artery Aneurysms: A Retrospective Cohort Study.

作者信息

Falzon Andrew, Miyake Shigeta, Kee Tze Phei, Andrade-Barazarte Hugo, Krings Timo

机构信息

Department of Neuroradiology, Atkinson Morley Regional Neuroscience Centre, St George's University Hospital, Tooting, London SW17 0QT, UK.

Department of Neurosurgery, Yokohama City University School of Medicine, Yokohama 236-004, Japan.

出版信息

Brain Sci. 2024 Dec 24;15(1):5. doi: 10.3390/brainsci15010005.

Abstract

Anterior choroidal artery (AChoA) aneurysms pose a challenge for both endovascular and clipping procedures. The eloquent territory supplied by the parent vessel has limited collateralization and its compromise can lead to significant morbidity. This study aims to analyze the clinical outcomes and procedure-related complications of clipping and endovascular treatment of AChoA aneurysms to aid physician decision making. Thirty-two ruptured and unruptured AChoA aneurysms that underwent catheter angiography at a single neurovascular center between January 2000 and December 2023 were included. Either conservative management, clipping, and/or endovascular treatment were performed. Clinical outcomes and complications were analyzed retrospectively. Twenty-four endovascular treatments and seven clipping procedures were included. Of the total 24 endovascular procedures, 46% were primary coiling, 25% were balloon-assisted coiling, 13% were flow diverting stent, 8% were combined balloon-assisted coiling and flow diverting stent, and 8% were combined balloon-assisted and stent-assisted coiling. There was no procedure-related mortality in both groups. No intra- or post-procedural ruptures/re-ruptures occurred during follow-up in both endovascular and clipping cohorts. AChoA territory infarcts occurred in 4% of the endovascular and 29% of the clipping cohorts. Other thromboembolic complications occurred in 4% of the endovascular cohort. The recurrence rate requiring retreatment was 12.5% for the endovascular and 43% for the clipping cohort. A favorable clinical outcome (mRS ≤ 2) was 78% for the endovascular cohort and 67% for the clipping cohort. Endovascular and clipping outcomes align with prior studies, with endovascular showing a favorable safety profile. Both approaches are viable, though they present distinct risks and advantages.

摘要

脉络膜前动脉(AChoA)动脉瘤对血管内治疗和夹闭手术都构成挑战。母血管供应的功能区侧支循环有限,其受损可导致严重的发病率。本研究旨在分析AChoA动脉瘤夹闭和血管内治疗的临床结果及与手术相关的并发症,以帮助医生做出决策。纳入了2000年1月至2023年12月期间在单一神经血管中心接受导管血管造影的32例破裂和未破裂的AChoA动脉瘤。进行了保守治疗、夹闭和/或血管内治疗。对临床结果和并发症进行了回顾性分析。包括24例血管内治疗和7例夹闭手术。在总共24例血管内手术中,46%为初次弹簧圈栓塞,25%为球囊辅助弹簧圈栓塞,13%为血流导向支架置入,8%为球囊辅助弹簧圈栓塞与血流导向支架置入联合应用,8%为球囊辅助与支架辅助弹簧圈栓塞联合应用。两组均无手术相关死亡。在血管内治疗组和夹闭组的随访期间,均未发生术中或术后破裂/再破裂。血管内治疗组4%的患者和夹闭组29%的患者发生了AChoA区域梗死。血管内治疗组4%的患者发生了其他血栓栓塞并发症。血管内治疗组需要再次治疗的复发率为12.5%,夹闭组为43%。血管内治疗组的良好临床结局(改良Rankin量表评分≤2)为78%,夹闭组为67%。血管内治疗和夹闭手术的结果与先前的研究一致,血管内治疗显示出良好的安全性。两种方法都是可行的,尽管它们存在不同的风险和优势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c47e/11763492/d54440491d15/brainsci-15-00005-g001.jpg

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