Turcotte Véronique, Guillaumie Laurence, Lemay Martine, Dionne Anne, Lemieux Julie, Labbé Angéline, Gotay Carolyn, Guénette Line, Lauzier Sophie
Population Health and Optimal Health Practices Axis, CHU de Québec-Université Laval Research Center, Hôpital du Saint-Sacrement, 1050 Chemin Ste-Foy, Québec, QC G1S 4L8, Canada.
Faculty of Nursing, Pavillon Ferdinand-Vandry, Université Laval, 1050 Avenue de la Médecine, Québec, QC G1V 0A6, Canada.
Curr Oncol. 2025 Jan 17;32(1):45. doi: 10.3390/curroncol32010045.
Adjuvant endocrine therapy (AET) is prescribed for 5-10 years to women with hormone-sensitive breast cancer to prevent recurrence. However, a significant proportion of women do not adhere to AET. We developed SOIE, a one-year program designed to enhance the AET experience and adherence. SOIE was pilot-tested in a mixed-methods randomized controlled trial. This report presents the experience of women and healthcare providers (HCPs) with SOIE.
A descriptive qualitative study using semi-structured interviews and thematic analysis was conducted with 20 women and 7 HCPs who participated in the program.
Most women and HCPs reported high satisfaction with the program. Women felt it addressed their need for information and strategies to manage side effects. They felt supported and developed a more positive attitude toward AET, which contributed to their intention to pursue AET. They perceived that the program helped them navigate the AET experience and reduced their stress or fear regarding AET. HCPs corroborated these benefits.
Findings suggest that SOIE can enhance the experience and motivation to pursue the AET treatment by meeting important needs for information, side-effects management, and psycho-emotional support. Programs like SOIE can have benefits beyond adherence by improving patients' well-being during this crucial long-term treatment.
激素敏感性乳腺癌女性患者需接受5至10年的辅助内分泌治疗（AET）以预防复发。然而，很大一部分女性并未坚持AET治疗。我们开发了SOIE，这是一个为期一年的项目，旨在改善AET治疗体验并提高治疗依从性。SOIE在一项混合方法随机对照试验中进行了试点测试。本报告介绍了女性患者和医疗服务提供者（HCPs）参与SOIE项目的体验。
采用半结构化访谈和主题分析进行描述性定性研究，研究对象为20名参与该项目的女性患者和7名HCPs。
大多数女性患者和HCPs对该项目表示高度满意。女性患者认为该项目满足了她们对信息及应对副作用策略的需求。她们感到得到了支持，并对AET治疗产生了更积极的态度，这促使她们打算坚持AET治疗。她们认为该项目帮助她们顺利完成AET治疗过程，并减轻了她们对AET治疗的压力或恐惧。HCPs证实了这些益处。
研究结果表明，SOIE通过满足患者对信息、副作用管理及心理情感支持的重要需求，可以改善AET治疗体验并增强患者接受AET治疗的动力。像SOIE这样的项目，除了提高治疗依从性之外，还能在这一关键的长期治疗过程中改善患者的健康状况，带来更多益处。
